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Necrotic Pulp clinical trials

View clinical trials related to Necrotic Pulp.

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NCT ID: NCT05348824 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars

Start date: August 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using Moringa oleifera leaf extract solution during chemo-mechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit

NCT ID: NCT05291195 Completed - Treatment Clinical Trials

Treatment of Young Permanent Teeth With Different Adjuvant Approaches

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

To determine microbiology assessment of infected root canal in young permanent teeth, as well as antimicrobial efficiency of different adjuvant treatment modalities including photodynamic therapy (PDT), high-power diode laser, and essential oils following mechanic-chemical treatment in the treatment of periapical periodontitis in these teeth.

NCT ID: NCT05289843 Not yet recruiting - Necrotic Pulp Clinical Trials

Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants

Start date: May 2022
Phase: N/A
Study type: Interventional

To measure the Effect of Rosmarinus Officinalis versus 2.5%Sodium Hypochlorite as Root canal Irrigants on the Intensity of post-operative pain and Bacterial Reduction in asymptomatic necrotic Mandibular premolars.

NCT ID: NCT05146713 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars

Start date: January 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using 20mg/ml propolis nanoparticles extract solution during chemo-mechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit.

NCT ID: NCT04983524 Completed - Necrotic Pulp Clinical Trials

Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp

Start date: October 2015
Phase: N/A
Study type: Interventional

Propolis is a resinous product of honeybees. Propolis is said to be effective against resistant microorganisms inside the root canal compared to the gold standard medication known as calcium hydroxide. The clinical trial tests the effect of propolis versus calcium hydroxide on pain in patients with necrotic teeth.

NCT ID: NCT04728386 Not yet recruiting - Necrotic Pulp Clinical Trials

Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite

Start date: January 2021
Phase: N/A
Study type: Interventional

This study aims to compare the effect of 2% curcumin solution versus 2.5% sodium hypochlorite as irrigating solutions in necrotic mandibular molars in terms of postoperative pain and antibacterial effect.

NCT ID: NCT04646538 Completed - Necrotic Pulp Clinical Trials

Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Start date: June 5, 2017
Phase: Early Phase 1
Study type: Interventional

3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.

NCT ID: NCT04606719 Completed - Necrotic Pulp Clinical Trials

Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical Periodontitis

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Earlier, it was believed that successful regeneration cannot be achieved once tooth has become infected. However, recent studies suggest that regenerative endodontics may in fact be possible in teeth with pulpal necrosis and periapical pathology. The primary goal in regenerative procedure is to eliminate clinical symptoms and resolve apical periodontitis. The blood clot acts as a scaffold, and the growth factors inside recruit stem cells, most likely from periapical papilla. But unfortunately, the erythrocytes in the clot of the blood column undergo necrosis, affecting its properties so the blood column is augmented by the use of different types of scaffolds. Platelet-rich fibrin is classified into four types (Standard PRF, Injectable PRF, Advanced PRF and Concentrated Growth Factor CGF) according to speed and time of centrifuge with the overall aim to increase the number of platelets and leucocytes

NCT ID: NCT04587089 Not yet recruiting - Necrotic Pulp Clinical Trials

Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth

Start date: August 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The maintenance of the deciduous tooth until its physiological exfoliation occurs is one of the main objectives of pediatric dentistry. Endodontic treatment in deciduous teeth resulting from carious or traumatic lesions with pulpal involvement is often necessary and we often find it difficult to perform it, due to the difficult control of the child, the internal anatomy of the root canals, and root resorptions. The non-instrumental endodontic treatment technique (TENI) associated with antimicrobial drugs has advantages such as shorter chair time and less complexity than the conventional technique in which root canal instrumentation is performed. The objective of this study is to carry out a controlled and randomized clinical trial to compare the effectiveness of non-instrumental endodontic treatment (NIET) in primary teeth associated with the use of two filling pastes. 120 necrotic deciduous teeth of children aged between 3 and 6 years will be selected; and the teeth will be divided into two groups. In Group 1 and Group 2, the root canals will not be instrumented, just irrigated and filled with the respective pastes, CTZ and Guedes-Pinto. The radiographic aspects will be evaluated, considering the repair process, clinically will be evaluated: presence of fistula and mobility, the evaluations will be carried out in both groups on the day of treatment and in periods of 1, 3 and 6 months after treatment. The data obtained will be submitted to the Shapiro-Wilk normality test, where the statistical analysis that will be used for this study will be defined, adopting a significance level of 95% (p<0.05).

NCT ID: NCT04262362 Recruiting - Pain, Acute Clinical Trials

The Frequency Of Sodium Hypochlorite Extrusion During Endodontic Treatments

Start date: December 5, 2019
Phase:
Study type: Observational

Sodium hypochlorite is a commonly used irrigation agent. However, the solution may extrude beyond the apex of tooth and cause pain during the treatment.The aim of this prospective observational investigation is to determinate the frequency of the extrusion of sodtium hypochlorite in endodontically treated teeth.