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Necrotic Pulp clinical trials

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NCT ID: NCT06418386 Completed - Necrotic Pulp Clinical Trials

Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars

Start date: September 12, 2022
Phase: N/A
Study type: Interventional

This study will evaluate and compare the microbial efficacy of rotary and manual filing system using Neem extract, NaOCL and saline . with hypotheses that neem can used alternative to sodium hypochlorite and there is no difference between rotary and manual filling in bacterial reduction.

NCT ID: NCT05775081 Completed - Necrotic Pulp Clinical Trials

Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

This study will be conducted to clinically evaluate the efficacy of human treated dentine matrix paste and Platelet rich fibrin (PRF) in induction of root formation of non-vital immature permanent teeth.

NCT ID: NCT05744661 Completed - Necrotic Pulp Clinical Trials

Mechanical Vs Chemomechanical Method For Calcium Hydroxide Removal

Start date: December 16, 2022
Phase: N/A
Study type: Interventional

Type of study: Randomised Clinical trial To compare the effectiveness of Mechanical and Chemomechanical methods in the removal of Water-based Calcium hydroxide medicament from endodontic system. Participants allocated in group A and B should be appointed for Endodontic treatment of Single rooted teeth diagnosed with Necrotic Pulp and Chronic Apical Periodontitis. In group A, Calcium hydroxide medicament will be removed by using Mechanical method while in group B, Calcium hydroxide will be removed by using Chemomechanical method.

NCT ID: NCT05291195 Completed - Treatment Clinical Trials

Treatment of Young Permanent Teeth With Different Adjuvant Approaches

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

To determine microbiology assessment of infected root canal in young permanent teeth, as well as antimicrobial efficiency of different adjuvant treatment modalities including photodynamic therapy (PDT), high-power diode laser, and essential oils following mechanic-chemical treatment in the treatment of periapical periodontitis in these teeth.

NCT ID: NCT04983524 Completed - Necrotic Pulp Clinical Trials

Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp

Start date: October 2015
Phase: N/A
Study type: Interventional

Propolis is a resinous product of honeybees. Propolis is said to be effective against resistant microorganisms inside the root canal compared to the gold standard medication known as calcium hydroxide. The clinical trial tests the effect of propolis versus calcium hydroxide on pain in patients with necrotic teeth.

NCT ID: NCT04646538 Completed - Necrotic Pulp Clinical Trials

Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Start date: June 5, 2017
Phase: Early Phase 1
Study type: Interventional

3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.

NCT ID: NCT04606719 Completed - Necrotic Pulp Clinical Trials

Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical Periodontitis

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Earlier, it was believed that successful regeneration cannot be achieved once tooth has become infected. However, recent studies suggest that regenerative endodontics may in fact be possible in teeth with pulpal necrosis and periapical pathology. The primary goal in regenerative procedure is to eliminate clinical symptoms and resolve apical periodontitis. The blood clot acts as a scaffold, and the growth factors inside recruit stem cells, most likely from periapical papilla. But unfortunately, the erythrocytes in the clot of the blood column undergo necrosis, affecting its properties so the blood column is augmented by the use of different types of scaffolds. Platelet-rich fibrin is classified into four types (Standard PRF, Injectable PRF, Advanced PRF and Concentrated Growth Factor CGF) according to speed and time of centrifuge with the overall aim to increase the number of platelets and leucocytes

NCT ID: NCT04018456 Completed - Clinical trials for Apical Periodontitis

Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical Periodontitis

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The aim of this prospective, randomized, controlled double-blind study is to evaluate the effectiveness of biodentine compared with MTA used as pulp space barrier on discoloration of teeth after regenerative based non-obturation root canal treatment in mature single canal with pulp necrosis and apical periodontitis.

NCT ID: NCT03708081 Completed - Pulpitis Clinical Trials

Comparative Evaluation of Different File Systems in Postoperative Pain

Start date: June 1, 2017
Phase:
Study type: Observational [Patient Registry]

Postoperative pain is a frequent complication associated with root canal treatment. The apical extrusion of irrigant and debris, including bacteria and necrotic tissue, may lead to postoperative pain, periapical inflammation, and flare-ups. The instrumentation technique and the file design may affect the amount of debris extrusion. The aim of this study was to evaluate the influence of instrumentation techniques on the incidence and intensity of postoperative pain after single-visit root canal treatment.

NCT ID: NCT03084601 Completed - Postoperative Pain Clinical Trials

Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy

3-mixtatin
Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

The aim of the current study is to compare a newly introduced material which is a combination of triple mix antibiotics paste and anti-hyperlipidemia drug simvastatin, the new material is named 3MIX-TATIN & will be compared to triple antibiotic paste for management of necrotic primary molars by using lesion sterilization and tissue repair LSTR technique.