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Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy of CC-486 in previously treated patients with locally advanced or metastatic nasopharyngeal carcinoma having failed one to two previous regimens, including platinum-based chemotherapy. Participants will be enrolled according to a Simon two-stage design; if the predefined activity is met (>4 responses [complete response; partial response {CR/PR}] out of the first 17 evaluable participants based on independent radiological assessment), then the study will continue to enroll an additional 34 participants. If 4 or less responses out of 17 are observed, then the study enrollment will be stopped.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02269943
Study type Interventional
Source Celgene
Contact
Status Completed
Phase Phase 2
Start date February 13, 2015
Completion date April 20, 2017

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