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Evaluating the Rationality of the International Guideline About Selective Coverage of Level Ib in CTV With NPC

Nasopharyngeal Carcinoma Clinical Trial

Official title:
Evaluating the Rationality of the International Guideline's Recommendations Regarding Selective Coverage of Level Ib in Node Clinical Target Volume With Nasopharyngeal Carcinoma : Results From a Real-world Series

Clinical Trial Summary

The purpose of this study was to evaluate its rationality in real-world data and provide clinical evidence for the refinement of nodal CTV delineation in nasopharyngeal carcinoma(NPC).

Clinical Trial Description

Intensity-modulated radiation therapy (IMRT) has gradually replaced two-dimensional radiation therapy as it offers improved target conformity. Xerostomia is still the most common side effect of radiotherapy in patients with NPC treated with IMRT. Most stimulated saliva is secreted by the parotid glands (PGs), while the submandibular glands (SMGs) produce most of the unstimulated saliva and mucins, which may influence the degree of a dry mouth sensation.There are still differences in the understanding of nasopharyngeal cancer experts at home and abroad on the delineation of clinical target volumes., suitable criteria for elective irradiation of neck level Ib need to be re-evaluated.Therefore, we conducted a retrospective study to assess the feasibility of recommendation to level Ib in the International Guideline for Delineation of Clinical Target Volumes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04745741
Study type Observational
Source Fujian Cancer Hospital
Contact Shaojun Lin, DR
Phone 13860603879
Email linshaojun@yeah.net
Status Not yet recruiting
Phase
Start date May 1, 2021
Completion date June 1, 2021
View Details
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