Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

Status Recruiting

Clinical Trial Summary

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

Clinical Trial Description

This is a prospective, parallel, randomized, open labeled, phase III, non-inferiority clinical trial to compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma patients in endemic area - nedaplatin, docetaxel and fluorouracil as induction chemotherapy regimen combined with nedaplatin as concurrent chemoradiotherapy (DNF-N) versus cisplatin, docetaxel and fluorouracil as induction chemotherapy regimen combined with cisplatin as concurrent chemoradiotherapy (DPF-P). All patients will receive radical intense modulate radiation therapy (IMRT). The primary endpoint is progress free survival (PFS). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04437329
Study type	Interventional
Source	Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Contact	Jinquan Liu, M.D
Phone	0086-137-1086-6485
Email	609149209@qq.com
Status	Recruiting
Phase	Phase 3
Start date	August 1, 2020
Completion date	June 30, 2029

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See also
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