KL-A167 Injection in Recurrent or Metastatic Nasopharyngeal Carcinoma

Status Completed

Clinical Trial Summary

The study is to evaluate the efficacy of KL-A167 injection in subjects with recurrent/metastatic Nasopharyngeal Carcinoma, as measured by Overall Response Rate (ORR) per the Response Evaluation Criteria in Solid Tumors RECIST Version 1.1

Clinical Trial Description

KL167-Ⅱ-05-CTP (NCT03848286) is a single-arm, open-label, multicenter, phase II study of KL-A167 in pts with R/M NPC. Eligible pts were diagnosed with histopathologically confirmed R/M nonkeratinizing NPC and had received ≥ two lines of chemotherapy. Pts received 900 mg KL-A167 every 2 weeks until disease progression, intolerable toxicity, or withdrawal of consent. The primary endpoint was overall response rate (ORR) evaluated by the independent review committee (IRC) according to Response Evaluation Criteria in Solid Tumors Version 1.1. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03848286
Study type	Interventional
Source	Sichuan Kelun Pharmaceutical Research Institute Co., Ltd.
Contact
Status	Completed
Phase	Phase 2
Start date	March 6, 2019
Completion date	January 13, 2022

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See also
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