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Hippocampus Avoidance During Intensity Modulated Radiotherapy for T4 Nasopharyngeal Carcinoma Patients

Nasopharyngeal Carcinoma Clinical Trial

Official title:
Hippocampus Avoidance During Intensity Modulated Radiotherapy for T4 Nasopharyngeal Carcinoma Patients:an Open, Prospective,Non-randomized Phase III Clinical Trial

Clinical Trial Summary

This is a prospective, non-randomized phase III study observing the cognitive function changes with conformal hippocampus avoidance during intensity modulated radiotherapy for T4 nasopharyngeal carcinoma patients.

Clinical Trial Description

All patients received intensity modulated radiotherapy or Tomotherapy with or without chemotherapy. Before radiotherapy, the patients will receive brain MRI scanning and the brain MRI images will be fused with the head and neck CT scan images. The investigators develop the treatment plan with hippocampus avoidance. Cognitive function are evaluated before,during and after radiotherapy. Dose-volume Histograms are got to analyze the associated factors. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03411954
Study type Observational
Source Zhejiang Cancer Hospital
Contact yuanyuan chen, professor
Phone +86 13738103808
Email chenyy@zjcc.org.cn
Status Recruiting
Phase N/A
Start date January 1, 2018
Completion date March 2022
View Details
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