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Nasal Surgery clinical trials

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NCT ID: NCT06305520 Enrolling by invitation - Nasal Surgery Clinical Trials

Medical Device Pivotal Study to Injection With SkinPlus-HYAL Implant Lidocaine vs RESTYLANE Lidocaine in of Nasolabial Folds

BPLUS-02
Start date: March 10, 2023
Phase: N/A
Study type: Interventional

Purpose : This investigation intends to demonstrate that the investigational device, SkinPlus-HYAL Implant Lidocaine, is non-inferior to the comparator device, RESTYLANE Lidocaine, in terms of temporary wrinkle reduction effect, safety, and injection site pain when applied on nasolabial folds in adults. Design : 24-week efficacy and safety evaluation and additional 48-week long-term safety and efficacy evaluation with a multi-center, randomized, subject- & evaluator-blind, matched pairs, active controlled, none-inferiority, confirmatory design Treatment Group: Application of the investigational medical device (SkinPlus-HYAL Implant Lidocaine) Control Group: Application of the comparator device (RESTYLANE Lidocaine) Population: Number of subject 100 * In this investigation, the same subject receives both test and control treatments, one on each side of the nasolabial folds (matched pairs design).

NCT ID: NCT05714540 Recruiting - Clinical trials for Nausea and Vomiting, Postoperative

Effect of Oropharyngeal Pack Soaked in Ketamine or Magnesium Sulphate on Post Operative Sore Throat After Nasal Surgery

Start date: February 15, 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the effect of ketamine or magnesium sulphate soaked throat pack on the incidence and severity of post operative sore throat as a primary outcome, post operative nausea and vomiting as a secondary outcome following elective nasal surgery under general anesthesia.

NCT ID: NCT05654311 Recruiting - Nasal Surgery Clinical Trials

Performance of EEG During Emergence Agitation in Nasal Surgery.

Start date: January 2, 2023
Phase:
Study type: Observational

The purpose of the study is to evaluate the relationship between perioperative electroencephalogram and emergence agitation in the nasal surgery. Previous studies showed that low frequency band wave activity increased during emergence delirium in pediatric patients. It is still not enough to explain the relationship between emergence agitation and electroencephalogram in adults. Researchers will demonstrate the relationship between parameters related electroencephalogram and emergence agitation in adults undergoing nasal surgery.

NCT ID: NCT05285566 Recruiting - Nasal Surgery Clinical Trials

Pain Control for Undergoing Costal Cartilage Harvesting

Start date: May 4, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.

NCT ID: NCT04819659 Completed - Anesthesia Clinical Trials

The Effect of Pharyngeal Packing on Postoperative Gastric Volume in Patients Undergoing Nasal Surgery

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Pharyngeal packing is a frequently used application to reduce the incidence and severity of postoperative nausea and vomiting (PONV) in patients who undergo nasal surgery. This study aims to research the effects of PP on gastric antral cross-sectional area (ACSA) and hence gastric volume as assessed by ultrasound, therewithal PONV and sore throat were evaluated as secondary outcomes in rhino logic surgeries (Septorhinoplasty, Septoplasty, Functional endoscopic sinus surgery).

NCT ID: NCT03036605 Completed - Nasal Surgery Clinical Trials

The Effect of Dexamethasone Added to Bupivacain in Nasal Surgery

Start date: March 15, 2017
Phase: Phase 4
Study type: Interventional

Nasal packing is frequently applied after nasal surgery. Nasal packing reduces epistaxis, prevents septal hematoma and stabilizes nasal septum. Nasal mucosa is quite sensitive to pain, therefore the most common problems after surgery are postoperative pain and anxiety during removal of the nasal packing. Lots of methods have been tried to control this pain (non-steroidal anti-inflammatory drugs, nerve blockade with long-acting local anesthetics, local anesthetics infiltration into nasal packing). Glucocorticoids have been used as an adjuvant in the management of acute postoperative pain. Perineural dexamethasone as an adjuvant for the single-injection nerve block can prolong analgesia and reduce opioid-requiring after surgery. Furthermore dexamethasone reduces postoperative nausea and vomiting incidance.

NCT ID: NCT01945502 Recruiting - PONV Clinical Trials

Nasopharyngeal Packing and Rhinologic Surgery.

Start date: September 2013
Phase: N/A
Study type: Observational

The purpose of this study is to assess the efficacy of three different pharyngeal packing during routine rhinologic surgery in the prevention of postoperative nausea and vomiting, and to evaluate the influence of pharyngeal packing on postoperative throat pain.

NCT ID: NCT00595608 Not yet recruiting - Nasal Surgery Clinical Trials

Sterimar vs Saline Sprays in Nasal Surgical Aftercare - a Blinded, Randomised Trial

Start date: February 2008
Phase: Phase 4
Study type: Interventional

Patients undergoing nasal surgery commonly experience a variety of symptoms in the post-operative period including blockage, running, pain, bleeding and reduction in sense of smell. A variety of preparations are currently recommended for symptomatic relief in the post operative period. These include saline irrigations and sniffs, steam inhalations, decongestants and steroid drops. There is currently no level 1 evidence in literature to support the use of any particular preparation over others in nasal surgical aftercare. We propose to conduct a single blinded, randomised trial comparing saline sprays vs Sterimar, a commercially available aerosolised isotone saline solution, comparing patients' symptom scores following septal surgery. The trial will help to establish efficacy and symptom control and advantages of one solution and delivery device over the other.