Nasal Polyposis Clinical Trial
Official title:
Exploration de l'Odorat en Imagerie Par Résonance Magnétique Fonctionnelle Chez Les Patients Atteints de Polypose Nasosinusienne
Nasal polyposis (NP) is a disease affecting 4% of the population. This disease is frequently accompanied by olfactory disorders (41%-84% of patients) that affect patients' quality of life. The aim of this study is to show brain activity differences in olfactory areas before and after surgery in each patient and between patient groups (normosmic, hyposmic and anosmic one) using functional Magnetic Resonance Imaging (fMRI). Brain activity will be measured by the intensity of brain signals and of the size of olfactory areas during olfactory stimulation before and after surgery. We suppose that fMRI could predict whether or not the patient will be able to recover smell after surgery.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04532736 -
Comparison of Methylprednisolone or Methotrexate in the Maintenance Treatment of Nasal Polyposis
|
Phase 2 | |
Completed |
NCT02784262 -
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis
|
Phase 2 | |
Active, not recruiting |
NCT04157335 -
Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID)
|
Phase 3 | |
Completed |
NCT02562924 -
The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery
|
N/A | |
Completed |
NCT00480298 -
Double-Blind Randomized Placebo-Controlled Trial on Clinical and Biological Effects of Oral Corticosteroids or Doxycyclin in Patients With Nasal Polyposis
|
Phase 2 | |
Completed |
NCT03358329 -
Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE)
|
Phase 3 | |
Active, not recruiting |
NCT01906697 -
The Effect of RF Turbinoplasty in Polypoid Change of Middle Turbinates
|
Phase 3 | |
Completed |
NCT03591068 -
Efficacy & Safety of OPN-375 Adults With Bilateral Nasal Polyps Using Nasoendoscopic Video
|
Phase 3 | |
Recruiting |
NCT05056714 -
Development of a Severity Assessment Score for Nasosinus Polyposis (PSI Score)
|
||
Completed |
NCT03401229 -
Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis
|
Phase 3 | |
Not yet recruiting |
NCT05131958 -
Nasality Evolution in a Nasal Polyposis Context : Multiparametric Evaluation : Articulatory (Imaging), Aerodynamics, Acoustics and Perception
|
||
Completed |
NCT02291549 -
S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps
|
Phase 3 | |
Completed |
NCT01393340 -
Clinical and Biological Effects of Anti-IgE (Omalizumab) in Patients With Bilateral Nasal Polyposis and Asthma
|
Phase 2 | |
Completed |
NCT02734849 -
Study to Evaluate Multiple Doses in Patients With Nasal Polyposis
|
Phase 2 |