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Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis — OSTRO  

Nasal Polyposis Clinical Trial

Official title:
A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study Of Benralizumab in Patients With Severe Nasal Polyposis

Clinical Trial Summary

The aim of this present study is to investigate the use of benralizumab as treatment for severe nasal polyposis. The effect of benralizumab on nasal polyps will be assessed over a 56 weeks of treatment period in patients with severe bilateral nasal polyposis who are still symptomatic despite standard of care therapy, i.e current use of intranasal corticosteroids (INCS) and prior surgery and/or use of systemic corticosteroids. The first 200 patients that complete the 56-week treatment will have a 6 month follow-up (FU) period without dosing.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03401229
Study type Interventional
Source AstraZeneca
Contact
Status Completed
Phase Phase 3
Start date January 15, 2018
Completion date July 31, 2020
View Details
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