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NCT06357052 Clinical Trial

The Study of Lithogenesis Processes in Patients With Non-alcoholic Fatty Liver Disease (NAFLD)

NAFLD Clinical Trial

— LINA  

Official title:
The Study of Lithogenesis Processes in Patients With Non-alcoholic Fatty Liver Disease (NAFLD)

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06357052
Other study ID # 2701
Secondary ID
Status Completed
Phase
First received
Last updated
Start date July 19, 2019
Est. completion date November 30, 2022

Study information
Verified date April 2024
Source Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease, ranging from pure steatosis to non-alcoholic steatohepatitis and ultimately to liver cirrhosis. In order to study the association between NAFLD and nephrolithiasis while minimizing the confounding effect of metabolic syndrome, we investigated the impact of different degrees of NAFLD severity on potential risk factors for stone formation.

Recruitment information / eligibility
Status Completed
Enrollment 42
Est. completion date November 30, 2022
Est. primary completion date April 30, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - subject >= 18 years old - able to sign the ICF - Liver biopsy with report compatible with NAFLD Exclusion Criteria: - alchol use > 20g/die - other causes of liver disease - active neoplasm

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Italy Fondazione Policlinico A.Gemelli IRCCS Roma

Sponsors (1)
Lead Sponsor Collaborator
Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Country where clinical trial is conducted

Italy, 

Outcome
Type Measure Description Time frame Safety issue
Primary the analysis of the correlation between the degree of severity of NAFLD And urinary lithogenic profilecharacterized by reduced urinary magnesium and altered urinary ammonium excretion. 15 years
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