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Myofascial Pain clinical trials

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NCT ID: NCT06036524 Recruiting - Myofascial Pain Clinical Trials

Multi-modal Imaging of Myofascial Pain

Start date: October 24, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to develop new imaging biomarkers for quantitative assessments of myofascial pain.

NCT ID: NCT05928884 Recruiting - Clinical trials for Chronic Low-back Pain

Ultrasound Imaging for Myofascial Pain

Start date: October 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to develop and validate a biomarker for lumbar myofascial pain (MP) based on ultrasound obtained measurements of the lumbar muscles and fascia. The investigators will use advanced machine learning approaches and validation in a randomized controlled trial. The main questions it aims to answer are: - Will the deep learning-based marker reliably identify subjects from the 4 different groups: healthy, MP without trigger points, MP with latent trigger points, and MP with active trigger points? - Will the deep learning-based marker accurately classify/predict the severity of MP in subjects with cLBP? Participants in the healthy group will be asked to do the following tasks: - Consent/Enrollment - Measure Height/Weight - Complete Questionnaires on REDCap - Participate in Ultrasound Imaging Experiment Sessions Participants in the chronic low back pain group will be asked to do the following tasks: - Consent/Enrollment - Complete Questionnaires on REDCap - Measure Height/Weight - Undergo a Standardized Clinical Exam - Participate in Ultrasound Imaging Experiment Sessions

NCT ID: NCT05876858 Recruiting - Myofascial Pain Clinical Trials

EXPLORER Total Body PET/CT Imaging for Myofascial Pain

Start date: June 13, 2023
Phase: Early Phase 1
Study type: Interventional

The main objective of this study is to establish novel measures derived from Total-body-Positron Emission Tomography/Computed Tomography (TB-PET/CT) as quantitative biomarkers for the investigation of myofascial pain. The TB-PET/CT assessed measures are those reflective of myofascial tissue metabolism, perfusion, and fatty infiltration.

NCT ID: NCT05793086 Recruiting - Clinical trials for Trigger Point Pain, Myofascial

Evaluation of a Novel Class of Objective Myofascial Pain Assessments

ENCOMPASS
Start date: January 27, 2023
Phase:
Study type: Observational

This is an observational study that is intended to determine the capacity of three technologies to serve as diagnostic biomarkers for myofascial pain syndrome. Investigators will seek patients with myofasical pain syndrome as well as healthy subjects for this study. Electrical impedance myography (EIM), myofiber threshold tracking (TT) excitability testing, and ultrasound with shear wave elastography (SWE) measurements will be obtained from the trapezius muscle (the muscle that extends over the back of the neck and shoulders). These measurements will be repeated within 2-5 days to assess repeatability of these methods.

NCT ID: NCT05562635 Recruiting - Clinical trials for Temporomandibular Disorder

CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)

Start date: July 18, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the project is to assess the effectiveness of reducing the masseter muscles tension and hyperactivity in patients with a painful form of TMD by using polymers containing CBD compared to placebo polymers.

NCT ID: NCT04775030 Recruiting - Clinical trials for Temporomandibular Disorder

Methodology for Developing an Occlusal Appliance With CBD Active Carrier

CBD-OCC-APP
Start date: January 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Evaluation of the efficacy of the occlusal appliance with active cannabidiol (CBD) molecules in TMD patients

NCT ID: NCT04546490 Recruiting - Neck Pain Clinical Trials

Effects of Release and Ischemic Pressure of Trigger Points on Neck Pain. A Crossover, Controlled and Randomized Trial.

Start date: February 15, 2020
Phase: N/A
Study type: Interventional

The aim of the study is to compare two manual therapy techniques. By testing if the Pressure Release of Myofascial Trigger Points technique (PRM) is more effective in treating Myofascial Trigger Points present in the upper trapezius muscle of patients with mechanical cervical pain. This will be compared mainly with another manual therapy technique that presents evidences such as Ischemic Pressure technique (IP), and a control group, through the evaluation of the Visual Analogical Scale (VAS), the Threshold of Pain at Pressure (TPP) and the Northwick Park Questionnaire (NPC) of neck disability, spanish version.

NCT ID: NCT03962556 Recruiting - Myofascial Pain Clinical Trials

Distribution of Trigger Points in Patient Who Have Myofascial Pain Disorder

Start date: December 15, 2018
Phase:
Study type: Observational

Myofascial pain alone covers 45.3% of the diagnosis of TMJ. It is defined as palpation sensitivity and regional muscle pain. Clinically muscle pain connects to myofascial trigger points.These trigger points are hypersensitive points located in a tense band of the skeletal muscle, which can be described, causing provoked or spontaneous pain. They are divided into two as active and latent. Those who cause spontaneous pain are active, and those who provoke pain are considered latent.Spasm in the chewing muscles with myofascial pain reduces the patient's pain threshold and quality of life. Therefore, patients with spasm and TMJ pain in the masticatory muscles should be examined for head and neck muscles, the presence of myofascial trigger points should be determined and the head and neck muscles should be included in physical therapy. The aim of this study was to determine the presence of myofascial trigger points in patients presenting with pain in the masticatory muscles and TMJ region, and to determine the relationship between the presence of trigger point and the degree of pain.

NCT ID: NCT03885791 Recruiting - Pelvic Pain Clinical Trials

Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain

Start date: March 22, 2019
Phase: N/A
Study type: Interventional

This is a placebo-controlled, randomized controlled trial to investigate the role of vaginal cryotherapy on pelvic floor myofascial pain in women. This study involves randomizing patients who are found to have pelvic floor myofascial pain on examination into one of two treatment groups: transvaginal cryotherapy or transvaginal application of a room-temperature tube. Patients will be followed up at two different time points in order to assess response to treatment. Follow-up times include immediately after application (Specific Aim #1) and two weeks following use of the intervention alone (Specific Aim #2). Patients will receive verbal and written instructions on using the intravaginal tubes by the research assistant who will not be blinded to treatment allocation. Patients will not be blinded to their treatment assignment but will not be given information on the alternative treatment. Patients will be referred to pelvic floor PT, which is considered the standard of care for treatment of pelvic floor myofascial pain at this time. As it typically takes 2-3 weeks to get in to see one of the pelvic floor PT providers at Wash U, follow up for this study will be completed prior to their attendance at pelvic floor PT. Patients will complete validated questionnaires assessing their pain, other pelvic floor symptoms, and acceptance of the intervention as a treatment option at the follow up time points.