COUREUR Study Myocardial Inflammation in Cyclist Part 1

Myocardial Inflammation Clinical Trial

Official title: Detection of Myocardial Inflammation in Cyclists After Strenuous Exercise: a Pilot Study Part 1

Status Completed

Clinical Trial Summary

The study will evaluate myocardial inflammation in cyclists after high intense and sustained exercise. Our hypothesis is that strenuous exercise in recreational cyclists may be associated with myocardial inflammation. Myocardial fibrosis in asymptomatic athletes is associated with life-threatening arrhythmic events and sudden death. Although myocarditis seems to be the most likely underlying cause, it remains unclear if strenuous and sustained physical exercise can cause myocardial inflammation with development of myocyte necrosis and possibly myocardial fibrosis in athletes.

Nineteen recreational cyclists performing "L'ETAPE DU TOUR (EDT) de France" a cycling ride (175 km, 3600 m of positive altitude difference) on July 4 2021 will be included in this study.

In part 1 of the study, each participant will complete a detailed questionnaire detailing their training history and an echocardiography at rest will be performed. All participants will have exercise testing approximately 1 week before the EDT stage to set aerobic and anaerobic gas exchange thresholds, as well as VO2max.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Inflammation
• Myocardial Inflammation
• Myocarditis

• NCT number: NCT04940650
• Study type: Interventional
• Source: Jessa Hospital
• Status: Completed
• Phase: N/A
• Start date: June 16, 2021
• Completion date: October 1, 2023