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NCT06038994 Clinical Trial

Prognostic Value of Surem TRAF3IP2 Level in Patients With Acute Myocardial Infarction

Myocardial Infarction, Acute Clinical Trial

Official title:
Prognostic Value of Surem TRAF3IP2 Level in Patients With Acute Myocardial Infarction

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06038994
Other study ID # 20230901
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date September 1, 2023
Est. completion date April 30, 2025

Study information
Verified date September 2023
Source Nanjing Medical University
Contact Jin Geng, MD.
Phone +86-17753124846
Email gj885258@163.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To evaluate the prognostic value of surem TRAF3IP2 levels in patients with acute myocardial infarction

Description:

Previous study had concluded that TRAF3IP2 plays a causal role in atherosclerotic plaque development and vulnerability in mice. However, no human data was available. In the present study, patients diagnosed with acute myocardial infarction who receive coronary angiography will be enrolled. Their surem TRAF3IP2 levels will be tested using ELASA. The association of surem TRAF3IP2 levels with the major adverse cardiac events will be evaluated.

Recruitment information / eligibility
Status Recruiting
Enrollment 200
Est. completion date April 30, 2025
Est. primary completion date April 30, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria: 1. Patients with acute myocardial infarction 2. patients received coronary angiography 3. invasive management within 72 h of hospital admission Exclusion Criteria: 1. NYHA III-IV 2. malignant tumor 3. acute infection 4. thyroid dysfunction 5. Life expectancy of b1 y 6. Unsuitable for PCI

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• No intervention
This is an obvertional study, and there is no intervention.

Locations
Country Name City State
China Huai'an First People's Hospital Huai'an Jiangsu

Sponsors (1)
Lead Sponsor Collaborator
Nanjing Medical University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary MACEs (major adverse cardiac events) MACEs were defined as a composite of cardiac death, hospitalization for myocardial infarction or heart failure 1 year
Secondary cardiac death and death due to cardiac reasons, such as myocardial infarction or heart failure 1 year
Secondary hospitalization for myocardial infarction or heart failure hospitalization for myocardial infarction or heart failure 1 year
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