Fetal Myocardial Performance Index in Diabetic Pregnancies

Status Completed

Clinical Trial Summary

The myocardial tissue is the most likely structure affected by hyperglycemia. The myocardial performance index (MPI) is a pulsed wave Doppler-derived index of global myocardial function. It is defined as the sum of the isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT) divided by the ejection time (ET) The fetal right heart contributes more to the cardiac output than the left heart; therefore, it is important to assess the right ventricular function. The investigators will measure right ventricular MPI in diabetic and normal pregnancies.

Clinical Trial Description

Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnancy, with an overall prevalence of 3-7 % during pregnancy. The myocardial tissue is the most likely structure affected by hyperglycemia. The myocardial performance index (MPI) is a pulsed wave Doppler-derived index of global myocardial function. It is defined as the sum of the isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT) divided by the ejection time (ET) The fetal right heart contributes more to the cardiac output than the left heart; therefore, it is important to assess the right ventricular function. The investigators will measure right ventricular MPI in diabetic and normal pregnancies. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03925064
Study type	Observational
Source	Kanuni Sultan Suleyman Training and Research Hospital
Contact
Status	Completed
Phase
Start date	August 1, 2018
Completion date	March 31, 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05081037` - Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)	N/A
Active, not recruiting	`NCT03249896` - Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes	N/A
Terminated	`NCT03749889` - Low Carb vs Normal Carb in Pregnancy	N/A
Completed	`NCT03859193` - Education Nutritional Video for Gestational Diabetics	N/A
Recruiting	`NCT05037526` - Utility of Real Time Continuous Glucose Monitoring in the Care of Gestational Diabetes Versus Standard Care in Pregnancy Outcomes	N/A
Completed	`NCT06178250` - Placenta, Fetal Liver, Sectional Ductus Venosus Volumes Examined by Three-dimensional Ultrasound in the Second Trimester	N/A
Not yet recruiting	`NCT06310356` - Continuous Glucose Monitoring for Women With Gestational Diabetes	N/A
Not yet recruiting	`NCT06445530` - Nutrition Optimization and Community Upliftment for Postpartum Recovery	N/A
Recruiting	`NCT02590016` - Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial	Phase 4
Withdrawn	`NCT01947699` - Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide	Phase 4
Not yet recruiting	`NCT00883259` - Metformin and Gestational Diabetes in High-risk Patients: a RCTs	Phase 4
Recruiting	`NCT03008824` - Micronutrients in Pregnancy as a Risk Factor for Diabetes and Effects on Mother and Baby	N/A
Active, not recruiting	`NCT01340924` - Relationship Between Gestational Diabetes and Type 2 Diabetes
Completed	`NCT00534105` - Lipid Metabolism in Gestational Diabetes	N/A
Recruiting	`NCT00371306` - Comparison of Glucovance to Insulin for Diabetes During Pregnancy	N/A
Completed	`NCT03388723` - Intergenerational Programming of Diabesity in Offspring of Women With Gestational Diabetes Mellitus
Recruiting	`NCT04521712` - Postpartum Glycemia in Women at Risk For Persistent Hyperglycemia	N/A
Enrolling by invitation	`NCT03307486` - Gestational Diabetes: a Cohort Study	N/A
Active, not recruiting	`NCT03301792` - Group Versus Traditional Prenatal Care for Diabetes	N/A
Enrolling by invitation	`NCT05603793` - YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition