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An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

Myelofibrosis Clinical Trial

Official title:
An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

Clinical Trial Summary

This is a phase I/II study evaluating the optimal dose of N-acetylcysteine (N-AC) in patients with myeloproliferative neoplasms (MPN).

Clinical Trial Description

This is a phase I/II open-label clinical trial determining the optimal biological dose (OBD) of N-acetylcysteine in subjects with myeloproliferative neoplasms. These are subjects who have a diagnosis of essential thrombocythemia (ET), polycythemia vera (PV), or myelofibrosis (MF). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05123365
Study type Interventional
Source University of California, Irvine
Contact Angela Fleischman, MD, PhD
Phone (714) 456-8000
Email agf@hs.uci.edu
Status Recruiting
Phase Phase 1/Phase 2
Start date January 3, 2022
Completion date November 15, 2026
View Details
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