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A Phase II Pilot Study to Assess the Presence of Molecular Factors Predictive for Hematologic Response in Myelodysplastic Syndrome Patients Receiving Deferasirox Therapy. — EXPHAR  

Myelodysplastic Syndrome Clinical Trial

Official title:
A Phase II Pilot Study to Assess the Presence of Molecular Factors Predictive for Hematologic Response in Myelodysplastic Syndrome Patients Receiving Deferasirox Therapy in Hematological Centers in Belgium Using Gene Expressing Profiling From Baseline Bone Marrow.

Clinical Trial Summary

Several previous studies (clinical and non-clinical) hypothesize that treatment with deferasirox causes a hematological improvement in transfused patients with low and intermediate-1 risk myelodysplastic syndrome. The purpose of this study was to assess the presence of genetic biomarkers predictive for hematologic response by the use of gene expression profiling of bone marrow aspirates obtained from MDS patients with or without hematological response.

Clinical Trial Description

This trial was terminated due to low enrollment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02663752
Study type Interventional
Source Novartis
Contact
Status Terminated
Phase Phase 2
Start date May 30, 2016
Completion date July 1, 2016
View Details
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