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Mycoses clinical trials

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NCT ID: NCT02912156 Completed - Fungus Infection Clinical Trials

Pharmacokinetics of Two Different Formulation of Voriconazole

Start date: June 2016
Phase: Phase 4
Study type: Interventional

A Randomized, Parallel, Single-Dose Study to Evaluate the Pharmacokinetics of Two Different Formulation of Voriconazole 200 mg Tablets in Healthy Adult Subjects.

NCT ID: NCT02888197 Completed - Mycoses Clinical Trials

Non-Interventional Extension to Investigate Recurrence of Vulvovaginal Candidiasis and Candida Colonization

Start date: August 16, 2016
Phase: N/A
Study type: Observational

Non-interventional extension study to investigate VVC recurrence and candida colonization following the P2 acute VVC study

NCT ID: NCT02883517 Completed - Clinical trials for Lymphoma, Large B-cell, Diffuse

Cell-free Circulating DNA in Primary Cutaneous Lymphomas

MATULILA
Start date: November 22, 2016
Phase:
Study type: Observational

To evaluate the possibility of detecting cell-free circulating tumoral DNA in potentially aggressive primary cutaneous lymphomas, the investigator opted to search a representative tumor sample mutation in the blood of these patients, by digital PCR. Patients with mycosis fungoides, primary cutaneous T-cell lymphoma helper follicular phenotype and primary cutaneous diffuse large B-cell lymphoma, leg-type will be included and 4 blood samples will be collected during 12 months.

NCT ID: NCT02859831 Completed - Mycosis Clinical Trials

Sautour PHRC IR 2008

SautourPHRCI08
Start date: n/a
Phase: N/A
Study type: Observational

Fusarium are microscopic filamentous fungi that live as saprobiontics in outside environments. They are found in the soil, the air, in water and on numerous plants. The frequency of fusariosis is currently increasing and Fusarium-related mycoses are the 3rd most frequent invasive mycoses. Most cases have been reported in the United States, in France, in Italy and in Brazil. A few epidemiological studies have shown the role of water in the appearance of mycoses in highly immunodepressed patients. Few studies have focused on the role of water in the transmission of mycoses in hospitals. The aim of this prospective study is to describe, in time and pace, the contamination by Fusarium sp. in the water of two different hospitals (Dijon, Nancy), by taking into account factors such as seasons and major works (reconstruction of a hospital). In each hospital, one reconstruction site will be compared with a site not under reconstruction (control). Water samples will be taken from the rooms of hospitalized patients.

NCT ID: NCT02851680 Completed - Clinical trials for Invasive Fungal Infections

Interest of ß 1-3 D Glucan Assays in Screening for the Onset of Invasive Aspergillosis in Neutropenic Patients With Acute Leukaemia.

BETA GLUCAN
Start date: September 2014
Phase: N/A
Study type: Interventional

In the context of screening for infectious fungal diseases in patients with malignant haemopathy, and particularly patients with acute leukaemia, the investigator aims to evaluate the performance of an already commercialized but little used serum screening test (Fungitell® test) and to determine its place in the management strategy for invasive aspergillosis.

NCT ID: NCT02823132 Completed - Acute Leukemia Clinical Trials

Study of the Level of a Protein Which Could Predict the Development of a Fungal Infection in Patients With Acute Leukemia

MBL INFFONG
Start date: n/a
Phase: N/A
Study type: Observational

The aim of this study is to investigate levels of a protein, mannose binding lectin, in patients with acute leukemia who develop or not an invasive fungal infection.

NCT ID: NCT02822586 Completed - Mycosis Fungoides Clinical Trials

TSEB and Brentuximab for Treatment of Mycosis Fungoides & Sezary Syndrome

Start date: December 19, 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the cutaneous toxicity and treatment response associated with administering concurrent TSEB and brentuximab vedotin in patients with mycosis fungoides or Sézary Syndrome.

NCT ID: NCT02805946 Completed - Clinical trials for Acute Graft Versus Host Disease

Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections

PIRAÑA
Start date: April 28, 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the the pharmacokinetics of posaconazole (new solid oral and IV) given as prophylaxis to patients who are at risk for developing fungal infections after receiving conditioning therapy (except strictly non-myeloablative (NMA)) for allogeneic Stem Cell Transplant (SCT), remission induction chemotherapy for acute myeloid leukemia (AML) or myelo dysplastic syndrome (MDS) or being treated for severe graft versus host disease (GvHD) and determines the impact of mucositis on the pharmacokinetics of posaconazole new solid oral.

NCT ID: NCT02734862 Completed - Fungal Infection Clinical Trials

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension

STRIVE
Start date: July 26, 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if intravenous CD101 is safe and effective in the treatment of candidemia and/or invasive candidiasis when compared to caspofungin (followed by oral fluconazole).

NCT ID: NCT02733432 Completed - Mycoses Clinical Trials

RADIANT: CD101 vs Standard of Care in Subjects With Acute Vaginal Yeast Infections

Start date: June 8, 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if two topical formulations of CD101 are safe and effective in the treatment of acute moderate to severe vulvovaginal candidiasis (VVC) compared to oral fluconazole.