Muscular Dystrophy Clinical Trial
— FSHD3Official title:
Study of Morphology and Functional Magnetic Resonance Imaging (MRI) Muscle Patients With Muscular Dystrophy Type FSHD Benefiting a Physical Training Introduced.
The safety of guided practice of physical activity in myopathies is increasingly accepted,
including muscular dystrophies. In facioscapulohumeral dystrophy (FSHD), one of the most
common muscular dystrophy, the aerobic training showed its physiological and functional
efficiency without affecting the quality of life of patients. The issue of exercise therapy
extended to all neuromuscular diseases, as has been rigorously analyzed, shows that the use
of a training program combining endurance exercise targeted exercises and strength is even
more relevant.
To complete the multidimensional assessments be managed by each team ( physiological
assessments, functional tissue and quality of life) it is relevant to continue , for a
descriptive study quantitative and qualitative analyzes by muscle imaging and spectroscopy
(MRI and Nuclear Resonance Imaging (NMR) spectroscopy ).
Status | Completed |
Enrollment | 15 |
Est. completion date | June 2015 |
Est. primary completion date | June 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Included in the FSHD1 and FSHD2 studies - Social Security regimen affiliated - Consent form signed Exclusion Criteria: - Severe cardiac or respiratory insufficiency - Cardiac pacemaker - Morbid obesity (BMI upper to 35) - Anti platelet therapy |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
France | CHU de Grenbole | Grenoble | |
France | CHU de Saint-Etienne | St Etienne |
Lead Sponsor | Collaborator |
---|---|
Centre Hospitalier Universitaire de Saint Etienne | Association Française contre les Myopathies (AFM), Paris, Ministry of Health, France |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Parameters of MRI | whole body imaging T1, T2-weighted | 30 months | No |
Secondary | Muscle tissue parameters | muscle biopsy | 30 months | No |
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