The Study of Skeletal Muscle Blood Flow in Becker Muscular Dystrophy

Status Terminated

Clinical Trial Summary

This pilot study tests the hypothesis that the medication nitric oxide extract from beetroot juice improves blood flow to the skeletal muscle during exercise. The investigators will use cutting edge technology with contrast enhanced ultrasound to visualize the microvascular blood supply to the forearm. Animal studies have shown reversal of muscle damage with improved delivery of blood to the exercising muscle. This research aims to understand the mechanism of action of this medication in a way it has never been studied before. The results may help benefit individuals with muscular Dystrophy in the future.

Clinical Trial Description

The subjects are asked to perform a graded hand-grip exercise while blood flow to the skeletal muscle is visualized by contrast enhanced ultrasound.

This is done at baseline and after taking the study agent. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02653833
Study type	Interventional
Source	Cedars-Sinai Medical Center
Contact
Status	Terminated
Phase	Early Phase 1
Start date	November 1, 2017
Completion date	September 1, 2018

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