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The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability — FAT-GAIT  

Muscle Spasticity Clinical Trial

Official title:
The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability

Clinical Trial Summary

Due to an early brain injury occurring in antenatal or postnatal, cerebral palsy (CP) causes alteration in motor function with posture and gait disorders. It is commonly observed motor performance degradation during adulthood, and the underlying pathophysiology remains poorly known.

Clinical Trial Description

One of the hypotheses to explain the decline in walking capacities in adults with CP is their greater fatigability, that could be related to energy overconsumption (due to the specific biomechanical constraints of their walking pattern) and/or the occurrence of early sarcopenia affecting the compensatory muscle mechanisms commonly seen in children to compensate for architectural disorders and posture alterations. To optimize prevention and/or therapy in these patients, it is crucial to better understand the aetiology of fatigability and its role in the decline in walking performance. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06163950
Study type Interventional
Source Centre Hospitalier Universitaire de Saint Etienne
Contact Bruno FERNANDEZ, MD
Phone (0)4 77 12 04 67
Email bruno.fernandez@chu-st-etienne.fr
Status Recruiting
Phase N/A
Start date May 2, 2023
Completion date October 31, 2024
View Details
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