Clinical Trials Logo

Clinical Trial Summary

Sometimes, during strenuous aerobic activity, activity ceases only when the discomfort that follows lack of oxygen would be intolerable. Reaching this fatigue condition can cause organ damage, muscular damage and / or in different tissues of the body. In this study, investigators aim at developing new indexes, based on hemodynamics measurements from the peripheral micro - circulation system, for the benefit of early detection of fatigue during accelerated physical activity.


Clinical Trial Description

14 healthy volunteers, 7 males and 7 females, aged 18-30 will participate in this study.The study includes 2 stages: In the first stage, aerobic capacity of the subjects will be measured by measuring maximum oxygen consumption (VO2max test). This phase will be conducted to determine physical measurements that could indicate different stages in muscle fatigue (anaerobic threshold, maximum oxygen consumption, heart rate and breathing indices).

In the second phase, the subjects will perform the same physical effort protocol that carried out at the first stage. Non- invasive measurements of leg muscles activity during aerobic exercise and at rest (before and after activity), will be carried out using a wireless EMG. Additionally, hemodynamic measurements of oxygen levels in the skin and skin perfusion monitoring before and after strenuous activity will be performed using two optic sensors. ;


Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic


Related Conditions & MeSH terms


NCT number NCT02691806
Study type Interventional
Source Sheba Medical Center
Contact Haggai Schermann, M.D
Phone +972828771014
Email Haggai.Schermann@sheba.health.gov.il
Status Not yet recruiting
Phase N/A
Start date March 2016
Completion date August 2016

See also
  Status Clinical Trial Phase
Completed NCT05077046 - Efficacy of an Ergonomic Handwriting Pen - The AWP Pen Study N/A
Recruiting NCT05073224 - Muscle Function After Childbirth N/A
Completed NCT03576391 - The Influence of Fatigue on Trunk Motor Control and Brain Activity N/A
Recruiting NCT05528250 - The Effect of Quadriceps Muscle Fatigue on Balance
Completed NCT02923102 - Effects of Recoverben® on Recovery After Exhaustive Exercise N/A
Completed NCT01962298 - Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex Phase 3
Recruiting NCT03460639 - Administration of Low-level Laser on Muscles of Mastication Following the Induction of Initial Fatigue N/A
Enrolling by invitation NCT04367727 - Effect of Light Emitting Diode Therapy on Muscle Fatigue N/A
Completed NCT05862987 - The Effect of Hydrogen Rich Water Intake on Acute Body Response and Following Recovery After 5 km Run in Untrained Men N/A
Completed NCT01932281 - SierraSil Joint Formula 14 as an Ergogenic Aid to Performance in Athletes N/A
Recruiting NCT01764620 - Effects of Muscle Fatigue and a Taping Technique on Shoulder Motion of Athletes N/A
Completed NCT03186573 - Effect of Grape Juice Consumption on the Parameters of Oxidative Stress and Muscle Fatigue in Judo Athletes N/A
Recruiting NCT03998280 - The Effect Of Cervical Muscle Fatigue in Neck Proprioception and Postural Stability
Completed NCT03863340 - Short Interventions to Prevent Trapezius Muscle Fatigue in Computer Work N/A
Completed NCT02014233 - Short Term Omega-3 Supplementation on Performance N/A
Completed NCT03712592 - Physiological Constraints Associated With Trail Running N/A
Recruiting NCT04082156 - The Effect of Transcutaneous Electrical Nerve Stimulation on People With Muscle Fatigue Due to Training, Sports N/A
Completed NCT04415099 - Tibialis Posterior Fatigue and Plantar Pressure N/A
Completed NCT02495428 - Effect of Kinesio Taping in Muscle Fatigue N/A
Completed NCT03342820 - Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients N/A