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Clinical Trial Summary

This prospective study is to characterize the genomic landscape and genetic heterogeneity of multiple synchronous lung cancer (MSLC) in correlation with comprehensive clinical, histopathological and medical imaging information, in order to improve disease diagnosis and tailored treatment for MSLC patients.


Clinical Trial Description

- To initiate a prospective registry of MSLC patients with high-quality clinical samples and detailed medical data.

- To define the clonal relationship, genomic landscape and potential driver alterations of MSLC using whole-genome sequencing.

- To determine the intrapatient and intratumor genetic heterogeneity of MSLC.

- To correlate molecular features with clinical parameters and patient outcome.

- To serve as a continuous infrastructure for a large variety of research purposes including: A. Diagnostic research B. Prognostic research C. Biological research D. Interventional trial design testing new therapies in MSLC. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03795155
Study type Observational
Source RenJi Hospital
Contact Pengfei Ma, Ph.D.
Phone +8613671806647
Email pengfei0820@163.com
Status Recruiting
Phase
Start date December 1, 2018
Completion date November 30, 2023