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Multiple Pulmonary Nodules clinical trials

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NCT ID: NCT06458673 Recruiting - Clinical trials for Multiple Pulmonary Nodules

A Prospective, Non-interventional Cohort Study of Subsolid Pulmonary Nodules

Start date: November 1, 2023
Phase:
Study type: Observational [Patient Registry]

Some studies have shown that the model for judging and predicting the growth of sub-solid pulmonary nodules through big data and deep learning can detect nodule growth earlier. Since most of the training data come from large foreign samples, most of the validated data are CT data from a single center or a few centers, and their generalization ability needs to be further verified. In order to better study subsolid pulmonary nodules in the lungs in China, we plan to conduct a prospective, multicenter, non-interventional observational cohort study.

NCT ID: NCT06426628 Recruiting - Lung Cancer Clinical Trials

Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

NIGHTINGALE
Start date: July 18, 2022
Phase:
Study type: Observational

The goal of this observational study is to learn how a physician uses the results of the Percepta® Nasal Swab test to manage people with a newly identified pulmonary nodule. The main questions it aims to answer are: - Does the use of the Percepta Nasal swab test reduce the number of invasive procedures in people with a low-risk result and whose nodule is benign? - Does the use of the Percepta Nasal swab test decrease the time to treatment in people with a high-risk result and whose nodule is cancer? Participants will be randomly assigned to either a group where the test result is provided to the physician (test arm) or to a group where the test result is not provided (control arm). Researchers will compare management of participants in the two groups.

NCT ID: NCT06335563 Recruiting - Pulmonary Nodule Clinical Trials

Augmented Reality Navigation Versus Traditional CT Guidance for Preoperative Localization of Pulmonary Nodules

Start date: March 14, 2024
Phase: N/A
Study type: Interventional

This study aims to conduct a large-sample randomized controlled clinical trial, using traditional CT-guided thoracic puncture localization as a comparison, to explore the accuracy, safety and clinical advantages of Intelligent AR glasses in assisting preoperative localizing of small pulmonary nodules.

NCT ID: NCT06308120 Recruiting - Lung Cancer Clinical Trials

A Trial to Compare Robotic Assisted Bronchoscopy Ion's Clinical Utility for Peripheral Lung Nodule Access and Diagnosis to ENB

ARTICULAtE
Start date: March 20, 2024
Phase: N/A
Study type: Interventional

Multi-center randomized controlled study designed to compare the diagnostic yield of ION™ Endoluminal System with electromagnetic navigation bronchoscopy in patients undergoing transbronchial sampling procedure of peripheral pulmonary nodules.

NCT ID: NCT06187935 Recruiting - Clinical trials for Pulmonary Nodules, Solitary

Early Adjuvant Diagnosis of Pulmonary Nodules Based on CTC.

Start date: March 1, 2018
Phase:
Study type: Observational

The goal of this observational clinical trial is to evaluate the value of circulating tumor cell detection in the early diagnosis of malignant pulmonary nodule. The main questions it aims to answer is: the sensitivity and specificity of peripheral blood circulating tumor cell detection in differentiating benign and malignant pulmonary nodules (<3cm). Participants will be asked provide 4mL of peripheral blood for the test.

NCT ID: NCT06074133 Recruiting - Pulmonary Nodule Clinical Trials

A Combined Biomarker Model for Risk Stratification of Indeterminate Pulmonary Nodules

Start date: March 7, 2024
Phase:
Study type: Observational

This is a prospective, multicenter observational study aim at estimating the potential clinical utility of the CBM and at establishing the SOPs and protocols for a future randomized control trial.

NCT ID: NCT06056999 Recruiting - Pulmonary Nodules Clinical Trials

New Method to Differentiate Benign and Malignant Pulmonary Nodules.

Start date: September 29, 2023
Phase:
Study type: Observational

The goal of this observational clinical trial is to establish a new method for differentiating benign and malignant pulmonary nodules by peripheral blood detection in patients with pulmonary nodules (<3cm). The main questions it aims to answer is: How to combine blood metabolomic mass spectrometry detection and artificial intelligence image analysis to establish a new model for differentiating benign and malignant pulmonary nodules. Participants will be asked provide 4 mL peripheral blood for the test.

NCT ID: NCT06056882 Recruiting - Pulmonary Disease Clinical Trials

Simultaneous CLE Guided Crybiopsy in Patients With Pulmonary Nodules

Start date: September 20, 2023
Phase:
Study type: Observational

It is planned to use the CLE probe and cryoprobe simultaneously after detection of the round focus. It is planned to include 5 patients with suspected central airway invading lung carcinoma and 15 patients with suspected peripheral lung carcinoma who have an indication for bronchoscopic histologic confirmation.

NCT ID: NCT06004440 Recruiting - Lung Cancer Clinical Trials

Real World Registry for Use of the Ion Endoluminal System

Start date: September 21, 2023
Phase:
Study type: Observational [Patient Registry]

The primary objective of this study is to evaluate the performance of the Ion Endoluminal System with real-world use for pulmonary lesion localization or biopsy.

NCT ID: NCT05968898 Recruiting - Lung Cancer Clinical Trials

Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES

ARCADES
Start date: January 9, 2024
Phase: N/A
Study type: Interventional

This is a pragmatic clinical trial that will study the effect of a radiomics-based computer-aided diagnosis (CAD) tool on clinicians' management of pulmonary nodules (PNs) compared to usual care. Adults aged 35-89 years with 8-30mm PNs evaluated at Penn Medicine PN clinics will undergo 1:1 randomization to one of two groups, defined by the PN malignancy risk stratification strategy used by evaluating clinicians: 1) usual care or 2) usual care + use of a radiomics-based CAD tool.