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NCT01937676 Clinical Trial

LDH as a Biochemical Biomarker to Predict Organ Failure in the Emergency Department Setting

Multiple Organ Failure Clinical Trial

Official title:
LDH as a Biochemical Biomarker to Predict Organ Failure in the Emergency Department Setting

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01937676
Other study ID # K3-akuten
Secondary ID
Status Completed
Phase N/A
First received August 30, 2013
Last updated September 3, 2016
Start date September 2013

Study information
Verified date September 2016
Source Karolinska Institutet
Contact n/a
Is FDA regulated No
Health authority Sweden: Regional Ethical Review BoardSweden: Swedish Data Inspection BoardSweden: The National Board of Health and Welfare
Study type Observational

Clinical Trial Summary

The purpose of this study is evaluate if K3, a novel biomarker, sampled at arrival to the emergency department can be used to predict the development of organ failure measured as SOFA score. K3 consists of lactate dehydrogenase, albumin and magnesium combined.

Recruitment information / eligibility
Status Completed
Enrollment 1250
Est. completion date
Est. primary completion date April 2014
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Age =18 years

- Admitted to emergency department, Karlstad Central Hospital, Sweden

Exclusion Criteria:

- Not in need of venous blood sample

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Sweden Karlstad Central Hospital Karlstad

Sponsors (1)
Lead Sponsor Collaborator
Karolinska Institutet

Country where clinical trial is conducted

Sweden, 

Outcome
Type Measure Description Time frame Safety issue
Primary Development of multiple organ failure Measured as SOFA score. 30 days or complete ICU stay No
Secondary Cardiac function Is it possible to predict cardiac function with the novel biomarker K3, which consists of lactate dehydrogenase, albumin, and magnesium combined? 30 days or complete ICU stay No
Secondary All cause mortality 30 days after admission to emergency department No
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