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Clinical Trial Summary

This study aims to determine the safety and the recommended phase II dose of RYZ101 (actinium-225 labelled DOTA-octreotate (225Ac-DOTATATE)) in participants with refractory and relapsing multiple myeloma (MM) that have received at least 3 prior lines of myeloma therapy. Participants will be selected based on somatostatin receptor (SSTR) positivity assessed by gallium-68 labelled DOTA-octreotate (68Ga-DOTATATE) PET/CT. The response to 225Ac-DOTATATE therapy will also be assessed in the target study population.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06411301
Study type Interventional
Source Jules Bordet Institute
Contact Wendy Delbart, PhD
Phone +3225413005
Email wendy.delbart@hubruxelles.be
Status Not yet recruiting
Phase Phase 1
Start date October 2024
Completion date October 2026

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