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Clinical Trial Summary

The goal of this clinical trial is to study the feasibility and efficacy of anti-CD19/BCMA bispecific chimeric antigen receptors (CARs) T cell therapy for relapsed and refractory multiple myeloma.


Clinical Trial Description

Primary Objectives

1. To determine the feasibility ad safety of anti-CD19/BCMA CAR-T cells in treating patients with BCMA-positive multiple myeloma.

Secondary Objectives

1. To access the efficacy of anti-CD19/BCMA CAR-T cells in patients with multiple myeloma.

2. To determine in vivo dynamics and persistency of anti-CD19/BCMA CAR-T cells. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03706547
Study type Interventional
Source Shanghai Zhongshan Hospital
Contact Zheng Wei, M.D.
Phone +(86)-21 64041990
Email wei.zheng@zs-hospital.sh.cn
Status Not yet recruiting
Phase Phase 1
Start date October 30, 2018
Completion date December 2021

See also
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