Can MicroRNA's Predict Multicentricity in Breast Cancer?

Multicentric Breast Cancer Clinical Trial

Official title:

Can MicroRNA's Predict Multicentricity in Breast Cancer?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04516330
• Other study ID #: MCBC-MIR
• Status: Completed
• Phase: N/A
• Start date: February 2014
• Est. completion date: April 2019

Study information

• Verified date: August 2020
• Source: Bezmialem Vakif University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to determine if microRNA's have role in predicting multicentricity in breast cancer. If a specific microRNA will be found to be related with multicentricity, it will help us to make appropriate decisions on the treatment of patients with multicentric breast cancer.

Description:

In the study that will be held at Bezmialem Vakif University Medical Faculty, General Surgery Department, 20 unifocal and 20 multifocal breast cancer patients will be included. Tissues will be taken from both tumoral and normal breast tissues and they will be saved in microRNA later solution under -80°C. Then, 84 microRNA's will be studied in these tissues to see if they express any of these microRNA's.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 57
• Est. completion date: April 2019
• Est. primary completion date: February 2016
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

1. Having breast cancer

2. Having no other malignancy

3. Female patient

Exclusion Criteria:

1. Having other malignancy

2. Under 18 years old

3. Male patient

Related Conditions & MeSH terms

• Breast Neoplasms
• Multicentric Breast Cancer

Intervention

Genetic:
• miRNA
miRNA's expressed in breast cancer

Locations

Country	Name	City	State
Turkey	Bezmialem Vakif University	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Bezmialem Vakif University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	MicroRNA's in multicentric breast cancer	Evaluation of 84 microRNA's in patients with multicentric breast cancer	April 2014
Secondary	Treatment plan according to the detected microRNA in patients with multicentric breast cancer	If a specific microRNA will be detected in patients with multicentric breast cancer, treatment plan will be individualized according to the detected microRNA	April 2014