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Clinical Trial Summary

The purpose of this study is to compare overall survival rates of colorectal cancer patients with multi-organ metastases with an indication for first line systemic treatment randomized for treatment with combination chemotherapy or treatment with combination chemotherapy and additional maximal tumor debulking including surgical tumor resection, RFA, (DEBIRI-)TACE and SBRT, depending on best clinical judgement according to a standardized treatment algorithm. Our hypothesis is that maximal tumor debulking in addition to systemic treatment with chemotherapy and biologicals will provide an improvement in progression free and overall survival in this patient group.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01792934
Study type Interventional
Source Radboud University Medical Center
Contact H.M.W. Verheul, MD PhD
Email orchestra.onco@radboudumc.nl
Status Recruiting
Phase N/A
Start date May 2013
Completion date July 2025

See also
  Status Clinical Trial Phase
Recruiting NCT06449937 - Local Liver Treatment for Multi-organ Colorectal Cancer Metastases N/A