Pain Clinical Trial
Official title:
Local Administration of Morphine: An Evaluation of the Analgesic Effect at Stomatitis in Children
Stomatitis/oral mucositis is a common side effect to chemotherapy. Stomatitis is often
associated with painful ulcers in the mouth. The study hypothesis is that morphine
administrated as a mouthwash can relieve stomatitis-related pain by a local analgesic
effect.
The purpose of this study is to test the analgesic effect of a morphine mouthwash versus
morphine injections or placebo (no active drug) in children/adolescents with stomatitis
related to chemotherapy. Besides the investigational drugs (morphine mouthwash and morphine
injections) the children/adolescents receive a standardized analgesic treatment for
stomatitis-related pain.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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