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Mucositis clinical trials

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NCT ID: NCT01420562 Recruiting - Clinical trials for Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Pharmacokinetics of Posaconazole in Allogeneic Transplant Patients With Mucositis

Start date: September 2011
Phase: N/A
Study type: Observational

The goal of this study is to calculate pharmacokinetic parameters and to evaluate the trough levels of posaconazole reached in patients with different stages of mucositis, due to chemotherapy and total body irradiation.

NCT ID: NCT01403064 Terminated - Oral Mucositis Clinical Trials

Safety and Efficacy of ALD518 for Reducing Oral Mucositis in Head and Neck Cancer Subjects

Start date: July 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of ALD518 in modifying the course of oral mucositis in subjects with head and neck cancer receiving concomitant chemotherapy and radiotherapy

NCT ID: NCT01402687 Completed - Multiple Myeloma Clinical Trials

SNP-Based Prediction of Oral Mucositis Risk in Patients Receiving Hematopoietic Stem Cell Transplants (HSCT)

Start date: October 2010
Phase: N/A
Study type: Observational

The goal of this study is to gain new knowledge about genetic risk factors thta may affect the development of mucositis, the chemotherapy-induced sores in the mouth and esophagus following HSCT. The study seeks to understand if different forms of genes result in an increased risk of sores in the mouth and esophagus.

NCT ID: NCT01400620 Completed - Oral Mucositis Clinical Trials

Safety and Efficacy of IZN-6N4 Oral Rinse for the Prevention of Oral Mucositis in Patients With Head and Neck Cancer

Start date: March 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether an oral rinse composed of botanical extracts is effective in the prevention of severe inflammation of the lining of the oral cavity caused by chemotherapy and radiation therapy for head and neck cancer.

NCT ID: NCT01385748 Completed - Oral Mucositis Clinical Trials

Efficacy and Safety Study of Clonidine Lauriad® to Treat Oral Mucositis

Start date: April 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Clonidine Lauriad® to treat chemoradiation therapy induced severe oral mucositis in patients with head and neck cancer.

NCT ID: NCT01375088 Completed - Clinical trials for Radiation-induced Mucositis of Oral Mucous Membranes

Assessing the Preventing and Therapeutic Effect of Propolis in Radiotherapy Induced Mucositis of Head and Neck Cancers

Start date: October 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether propolis is effective in the treatment and prevention of radiotherapy induced oral mucositis.

NCT ID: NCT01341054 Completed - Mucositis Clinical Trials

Use of Chamomilla Recutita in Mucositis

Start date: January 2011
Phase: N/A
Study type: Interventional

To determine the Chamomilla recutita solution dose needed to reduce the intensity and evolution time of oral mucositis in adult subjects submitted to HSCT.

NCT ID: NCT01321307 Not yet recruiting - Mucositis Clinical Trials

Aphtostomatitis and Mucositis Treatment by Natural Herbal Formula (Sorend®)

Start date: April 2011
Phase: N/A
Study type: Observational

Sorend is a water-based formula, which contains carob, melissa and sage. Elder inhabitants of Israel are known to use carob extract to ease sores in the mouth, due to the tannins which create a complex with various proteins and polysaccharides, thus creating an impenetrable layer covering the sores, allowing spontaneous healing.

NCT ID: NCT01318889 Recruiting - Clinical trials for Oral Mucositis (Ulcerative) Due to Radiation

Dexpanthenol Mouthwash to Treat Oral Mucositis

Start date: September 2010
Phase: Phase 2
Study type: Interventional

Oral mucositis can be a significant problem for cancer patients. It is typically associated with pain and increased risk of infection and can lead to impaired nutritional status and inadequate hydration.it can be seen in the patient population receiving high-dose head and neck radiation therapy (85%-100%). Topical dexpanthenol acts like a moisturizer, improving stratum corneum hydration, reducing transepidermal water loss and maintaining skin softness and elasticity. The stimulation of epithelization, granulation and mitigation of itching were the most prominent effects of formulations containing dexpanthenol. The investigators suppose that dexpanthenol mouth wash may improve oral mucositis.

NCT ID: NCT01305200 Completed - Clinical trials for Chronic Myelomonocytic Leukemia

Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant

Start date: March 2011
Phase: Phase 3
Study type: Interventional

This randomized phase III trial is studying how well Caphosol rinse works in preventing mucositis in young patients undergoing autologous or donor stem cell transplant. Supersaturated calcium phosphate (Caphosol) rinse may be able to prevent mucositis, or mouth sores, in patients undergoing stem cell transplant.