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Mouth, Edentulous clinical trials

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NCT ID: NCT05260892 Recruiting - Clinical trials for Edentulous Alveolar Ridge

Incisors Single-Unit Rehabilitation With Narrow GM Implants

Start date: October 1, 2022
Phase:
Study type: Observational

The Narrow GM Implants were designed for oral functional rehabilitation using dental implants, allowing for treatment of patients with different bone qualities in the region of lateral incisors in the maxilla or the region of lateral and central incisors in the mandible. The objective of the study is to confirm the long-term safety and clinical performance of implants and abutments of the Narrow GM System in a daily dental practice setting, by means of a prospective collection of clinical data in an observational study using these devices. Devices will be used according to standard routine in daily practice, according to all indications as specified by the manufacturer in the instructions for use (IFU). 55 patients (needed to obtain a sample size of 55 implants) will be followed for 36 months and monitored for Adverse Events by the Investigators until the last protocol-related procedure of a patient is completed.

NCT ID: NCT05241548 Recruiting - Clinical trials for Edentulous Alveolar Ridge

BMAC on PCL Scaffold for Ridge Augmentation

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

BMAC is used on 3D printed PCL scaffold for horizontal ridge augmentation in aesthetic zone , BMAC contains MSCs which can differentiate in osteogenic medium into osteoblasts which can lay down bone

NCT ID: NCT05141331 Recruiting - Clinical trials for Edentulous Alveolar Ridge

Comparison of Piezoelectric Split-crest Technique Versus Expansion Using Hand Driven Ridge Expanders in Treatment of Maxillary Narrow Ridges

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

Comparison of Piezoelectric split-crest technique versus expansion using Hand Driven Ridge Expanders in treatment of Maxillary Narrow Ridges

NCT ID: NCT05096624 Recruiting - Clinical trials for Disorder of Maxillary and Mandibular Dental Arch Relationship

Impact of Complete Removable Prosthetic Rehabilitations Performed by an Innovative DDTENS Protocol, on the Quality of Masticatory Function and the Management of Completely Edentulous Patients

DD-TENS
Start date: February 25, 2022
Phase: N/A
Study type: Interventional

Total edentulism is a profound physical, psychic and social handicap, which affects 5 million people in France. The most frequent complaint of edentulous patients rehabilitated by conventional Complete Removable Prostheses (CRP) is the reduction of masticatory efficiency. This alteration has medical repercussions and a negative psychological and social impact. Our study aims to evaluate the impact of an innovative protocol on the quality of masticatory function, prosthetic treatment and, in fact, on the quality of life of the totally edentulous patient. This protocol combines the Digital Denture system with the transcutaneous electrical neurostimulation system (TENS®), in order to improve the balance of the dento-dental contacts of CRP. This new protocol is called DDTENS. The first objective of the study is to compare the activity and balance of the masticatory muscles at 1 month (T1) of wearing the prostheses, between an experimental group benefiting from a CRP by the DDTENS protocol and 2 reference groups ( the first benefiting from a CRP by the conventional procedure and the second by the Digital Denture procedure) in bimaxillary total edentulous patients The secondary objectives are: - to compare the number of sessions required to obtain a finalized bimaxillary total removable prosthesis between the 3 groups. - to compare the quality of life of patients with their CRP between the 3 groups, at 1 month and 4 months of wearing the prostheses. - to compare the activity and balance of the masticatory muscles when the prostheses were put in the mouth (T0) and at 4 months (T4) of wearing the prostheses The study design is a randomised open-label controlled pilot study with blinded reviewer assessment comparing 3 parallel groups: - Experimental group: 10 bimaxillary edentulous patients rehabilitated by CRP using the DDTENS protocol. - Control group 1: 10 edentulous bimaxillary patients rehabilitated by CRP according to the conventional method (gold standard technique). - Control group 2: 10 edentulous bimaxillary patients rehabilitated by CRP using the Digital Denture procedure. The expected benefits for patients in the DDTENS experimental group are the optimization of occlusal balance, the optimization of the time of integration of the prosthesis in the mouth, the time saving in the prosthetic treatment of the edentulous patient and the improvement of eating behaviours and quality of life of edentulous patients which would delay the entry of our patients into the sphere of dependence. These results would allow the validation of a new rehabilitation protocol for the edentulous patient, leading to a modification of clinical practices.

NCT ID: NCT05081284 Recruiting - Clinical trials for Edentulous Alveolar Ridge

Clinical Outcomes of Immediate Implants With or Without a Volume-stable Collagen Matrix

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the soft tissue clinical results in patients that received, or not, a soft tissue augmentation around dental implant inserted immediately after the extraction.

NCT ID: NCT04915677 Recruiting - Clinical trials for Edentulous Alveolar Ridge

Edentulous Sites Augmented With Collagen Matrix or CTG

Start date: June 10, 2021
Phase: N/A
Study type: Interventional

Ridge deformities can complicate prosthetic rehabilitation, especially in situations where optimal esthetic outcomes are desired. Simpler, less invasive and predictable treatments are needed in order to obtain soft tissue augmentation at edentulous ridges. Autogenous subepithelial connective tissue graft (SCTG) has always been regarded as the treatment of choice, but heterologous volume stable collagen matrix (VCMX) is emerging as a reliable alternative. The principal aim of the present RCT will be to compare the volumetric buccal soft tissue changes at edentulous areas after augmentation procedure using VCMX or SCTG. Parameters related to periodontal health at adjacent teeth and patient reported outcomes (PROMs) will be also assessed as secondary outcomes. Proving the non- inferiority of VCMX compared to SCTG would provide the specialists and general clinicians with an easier, less invasive and better tolerated technique for soft tissue augmentation at edentulous ridges and for improving aesthetic and cleansability of the prosthetic rehabilitation.

NCT ID: NCT04429373 Recruiting - Clinical trials for Dental Implant Failed

Effect of Platelet-rich Plasm (PRF) on Two-implant Mandibular Overdenture: a Split Mouth

PRF
Start date: November 30, 2020
Phase: N/A
Study type: Interventional

Implant retained overdentures are a cost-effective treatment for elderly patients suffering from complete tooth loss. Despite the high success rate of implants in the general population, older adults lacking all teeth are a challenging population for implant therapy, often presenting limited bone disponibility, narrow alveolar ridges, diminished bone density, scarce inserted gingiva and several co-morbidities.Thus, improving their possibility of success in implant therapy avoiding further surgical interventions is key. Platelet-rich fibrin (PRF) is a blood derivate that can be easily and economically obtained from patients and that has shown promise of reducing the complications and improving the success of implant therapy, nevertheless its benefits in patients receiving implant retained overdentures has not been stablished. It is possible that PRF can improve the results and diminish the complications of implant therapy in older adults. The investigation aims to demonstrate that the use of platelet-rich fibirn (PRF) is safe and beneficial for implant treatment in older adults suffering from complete tooth loss.

NCT ID: NCT03543618 Recruiting - Clinical trials for Atrophy of Edentulous Alveolar Ridge

Evaluation of Dental Implant Placement in the Sloped Alveolar Ridge

Start date: March 15, 2018
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the therapeutic effect of sloped dental implants. It can reduce the need of osteoectomy, reduce discomfort of procedures, and is easier for maintenance.

NCT ID: NCT03536468 Recruiting - Partial Edentulism Clinical Trials

Psychological Impact of Tooth Loss

Edentpsy
Start date: January 25, 2019
Phase:
Study type: Observational

Tooth loss impact on daily living, mood and self-perceived well-being. However, psychological impact of teeth loss has not been evaluated. Present study aims to evaluate the psychological conditions of patients pending complete tooth extraction before and shortly after tooth loss using Hospital Anxiety and Depression scale (HAD) and Geriatric Oral Health Assessment Index (GOHAI).

NCT ID: NCT02850458 Recruiting - Edentulous Clinical Trials

Clinical Results of Implant-retained Mandibular Overdentures in Edentulous Patients

Start date: February 2016
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the clinical results of implant-retained mandibular overdentures in edentulous patients.