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Mouth, Edentulous clinical trials

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NCT ID: NCT06460103 Not yet recruiting - Clinical trials for Partially Edentulous Mandible

Peri-implant Bone Formation of Grafted Sites Around Hydrophilic and Non-hydrophilic Dental Implants

Start date: July 2024
Phase: N/A
Study type: Interventional

Although bone grafting at the same time as the placement of dental implants is a common procedure in implantology, there are currently no data on the influence of different types of implant surfaces on bone healing, which is crucial for implant stability. The primary objective of this study is to assess if implant surface properties, i.e. hydrophilicity, affect the osseointegration of the implant in simultaneously augmented bone. The secondary objective is to assess if implant surface properties, i.e. surface hydrophilicity, may affect the quantity of newly formed bone in the implant in simultaneously augmented bone. Surface hydrophilicity modification is a well-adapted concept in dental implantology and is clinically well-established. In this prospective study, all participants will receive a bone graft after extraction. After randomization, one group will receive a provisional SLA surface implant and another group will receive a provisional SLActive surface implant. The same standard surgical procedure will be performed for both groups when the definitive implant will be placed. The study will run for a total of 3 year, and 35 patients per group will be included. The Straumann SLA and SLActive implants, Maxgraft allograft and collprotect collagen membranes used in this study are all approved products on the Swiss market.

NCT ID: NCT06458738 Not yet recruiting - Edentulous Mouth Clinical Trials

Clinical Evaluation of a New Printable Denture Base Material

Start date: October 2024
Phase: N/A
Study type: Interventional

This clinical investigation is conducted to prove the long-term clinical performance of a new printable denture base material. The aim of this study is to assess the failure rate, the quality and functionality of the full dentures made with the printable denture base material over an investigational period of 5 years.

NCT ID: NCT06449443 Not yet recruiting - Clinical trials for Edentulous Alveolar Ridge

Zero Echo Time MR for the Assessment of Maxillary Sinus and Dental Regions

ZTE-DENTAL
Start date: June 1, 2024
Phase:
Study type: Observational

The aim of this study is to evaluate the efficacy of zero echo time magnetic resonance imaging (ZTE MRI) as an ionizing radiation-free diagnostic method to evaluate both hard and soft tissues and maxillary sinus region before dental implants in the posterior maxillary region.

NCT ID: NCT06417788 Recruiting - Clinical trials for Partially Edentulous Patients

Dynamic Guided Implant Surgery VS Static Guided Surgery.

Start date: May 30, 2024
Phase: N/A
Study type: Interventional

This study aims to evaluate if dynamic-guided surgery is an accurate system for placing dental implants. Researchers will assess the dental implant accuracy of the dynamic guided system compared to the static pilot guide. Participants will: - Receive implant treatment that will be placed by a dynamic or static pilot drill guided system. - Receive post-operative radiological exam for comparative (on the same appointment).

NCT ID: NCT06400277 Completed - Edentulous Jaw Clinical Trials

In-Vivo Comparison of Different Impression Methods in Complete Edentulous Upper Jaw

Start date: July 30, 2022
Phase: N/A
Study type: Interventional

In this study, it was aimed to compare the impressions taken with different impression techniques for the production of tissue-supported complete dentures from individuals with complete edentulous upper jaws. For this purpose, 15 individuals with complete edentulism in the upper jaw were asked to participate in the study. In addition to agreeing to participate in the study after reading the consent form, these individuals should have been using tissue-supported complete dentures in the upper jaw for at least 3 months. They should also have healthy mucosa without local factors such as tissue hyperplasia, atrophic crests, allergic reaction, epulis fissuratum. A total of five final impressions will then be taken from these individuals in two sessions. Two of these impressions will be obtained with the traditional method and three with the digital method. The traditional impression group will include one-step (ALG) and two-step (ZOE) impression techniques. The digital impression group will include the digital impression taken when the artificial intelligence is deactivated (A.I OFF), the digital impression taken when the artificial intelligence is activated (A.I ON) and the modified technique (MOD). In the first appointment, the first impressions will be taken for the traditional and digital groups. Intraoral exclusion and isolation will be provided before the digital first impression. With the A.I mode of the intraoral scanner (TRIOS4; 3Shape A/S, Copenhagen, Denmark) deactivated, scanning will be performed in accordance with the scanning protocol recommended by the company. A metal stock tray suitable for the dental arch will then be selected for the preliminary impression of the traditional impression group. The impression will be taken in one step with irreversible hydrocolloid impression material. The impression will be digitized with the same intraoral scanner within the first 10 minutes after impression taking. Both impressions will be digitally transferred to the dental laboratory as stl data. Using computer aided design (CAD) software (Exocad DentalCAD 2.4 Plovdiv), an individual tray will be designed for the ZOE impression in the traditional group and a pedestal for the MOD impression in the digital impression group. The designs will be transferred to the computer aided manufacturing (CAM) unit and produced with a 3D printer using dental resin. The occlusal-rim (OR) will be prepared by adding wax on the base. In the second appointment, the cheek and lips will be excluded in the same way before scanning. For A.I OFF and A.I ON, recordings will be taken when the artificial intelligence is deactivated and activated, respectively. Then, occlusal vertical dimension, intermaxillary relationship and aesthetic parameters will be determined with OR before scanning for the MOD group. Reference areas will be created on the buccal and palatinal walls to facilitate scanning of the OR. To avoid retention problems during scanning, a silicone-based impression material with a fluid consistency will be applied to the tissue surface of the OR and placed in the mouth. Scanning will be performed according to the protocol proposed by Lo Russo et al. For the traditional impression group, the ALG impression will be taken with a metal stock tray using irreversible hydrocolloid impression material in a single step. The impression will be digitized with an intraoral scanner within ten minutes of completion. Then, the edges of the individual tray for ZOE will be shaped with impression compound to ensure peripheral closure. The impression will be completed with zinc-oxide eugenol impression material. The impression will be digitized. These measurements will then be compared using a reverse-engineering program (Geomagic design X version 2016.1.0, 3D Systems Inc. Rock Hill, SC). Before the comparison, in the same program, the parts to be evaluated on the ZOE in the conventional group and A.I OFF in the digital group will be divided into regions. These areas will be divided into four sections as right and left vestibular region, postdam area, hard palate region, except for the A.I OFF-MOD comparison group. In the A.I OFF-MOD comparison group, it will include the right and left initial areas, including the areas where scanning starts in the second scan of the MOD method. In addition, all measurements will be compared in terms of the whole surface and all measurement boundaries including the whole measurement surface as one. The comparison groups are ZOE-ALG, ZOE-A.I OFF, A.I OFF-A.I ON, A.I OFF-MOD. The measurements in the comparison groups will be overlapped first with the initial alignment and then with the best fit alignment algorithm. All sections will be evaluated individually with the "3D compare" feature and the amount of deviation in the areas to be evaluated will be determined.

NCT ID: NCT06393582 Not yet recruiting - Dental Implants Clinical Trials

Accuracy Evaluation of Implant Impressions: A Prospective Study

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The aims of this clinical study are: 1) to compare the accuracy of conventional versus digital impression techniques for implant impressions; 2) to assess the passive fit of the prosthesis constructed from the most accurate impression. Thirty edentulous patients who received 4 - 6 implant and indicated for implant-supported fixed prosthesis will be invited. Full-arch conventional and digital impressions will be made for each patient. Accuracy evaluation will be made and the prosthesis will be constructed from the most accurate impression. Passive fit of the zirconia implant-supported prostheses will be verified at the try-in stage clinically and radiographically.

NCT ID: NCT06378112 Recruiting - Clinical trials for Edentulous Alveolar Ridge With Labial Resorption

Extraction Socket Augmentation. A Clinical Study

GTO
Start date: May 20, 2022
Phase: Phase 4
Study type: Interventional

Extraction socket preservation is defined as alveolar ridge preservation within the bone envelope remaining after tooth extraction, meanwhile ridge augmentation is defined as increasing the volume of alveolar ridge beyond the bony envelope at the time of tooth extraction. It is recommended to use in cases where extraction socket anatomy is intact. In contrast definition "extraction socket augmentation" defines alveolar ridge restoration when bony walls of the socket are partly or completely lost. In the case of severe loss (> 50%) of the buccal bone plate, preservation of hard tissue with a prolonged healing time before implant placement has been suggested. The null hypothesis of this experimental work states that: (i) the two different bone graft materials gained the same amount of bone following horizontal ridge augmentation procedure; (i) the two different bone graft materials exhibit similar histological and histomorphometric results Therefore, the main purpose of the current study is to compare two different biomaterials using guided bone regeneration procedures in the ridge preservation/ augmentation (hard-tissue preservation).

NCT ID: NCT06349525 Completed - Jaw, Edentulous Clinical Trials

Retention of Telescopic Versus Locator Attachments

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Forty patients ( 24female and16 male )with completely edentulous maxilla and mandible . All patients received implant supported mandibular and maxillary overdentures. The patients were randomly divided into two groups according to attachments retaining Max IOD that supported by four axial implants in maxilla . The TA was used to retain group I (GrI) MaxIOD , while that of group II (Gr II) was retained by LA. MaxIOD retention and MBL(vertical and horizontal) around implants of both groups was recorded at time of insertion (R0) ,then twelve(R12)and (R24) months following insertion of the prosthesis.

NCT ID: NCT06343441 Not yet recruiting - Edentulous Jaw Clinical Trials

Accuracy of Two Methods of Making Impressions for Complete-arch Implant Supported Fixed Prosthesis

Start date: March 31, 2024
Phase: N/A
Study type: Interventional

To compare the accuracy of digital impression and conventional impression for complete-arch implant-supported fixed prosthesis

NCT ID: NCT06334770 Completed - Clinical trials for Completely Edentulous Patients

Influence of Roxolid Implant Material on the Implant Stability Implant Stability

BLX
Start date: June 15, 2021
Phase: N/A
Study type: Interventional

Fourteen completely edentulous patients were selected to participate in this study. From the outpatient clinic of Prosthodontic Department, Faculty of Dentistry, Ain Shams University. After fabrication of complete denture for all patients, patients were randomly divided to: Group A: Seven patients were rehabilitated with implant retained maxillary overdenture where four Straumann BLX® implant were inserted opposed by mandibular complete denture. Group B: Seven patients were rehabilitated with implant retained maxillary overdenture where four conventional acid etched implants were inserted opposed by mandibular complete denture. After implant placement using surgical guide, smart peg and ostell device were used to measure the primary stability of the implant then cover screw was placed and after six weeks, secondary stability was measured for both groups. After four months, the second stage started in which exposure of the implant fixtures took place and pick up was carried out. Patients were recalled frequently for post-insertion inspection and adjustment.