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Clinical Trial Summary

This study will begin to evaluate personalized preventative dementia treatments for Veterans at risk for developing dementia. The investigators will target Veterans with Motoric Cognitive Risk syndrome (MCR), which is characterized by slow gait speed and cognitive concerns (e.g., problems with memory or concentrations).


Clinical Trial Description

This study will involve therapeutic exercise treatments for Veterans with pre-clinical dementia syndrome. Participants will either participate in functional power training, music-based walking training, or a combination of both. The study will use a sequential multiple assignment, randomized trial (SMART) design. Successful completion of this study will lay the foundation for subsequent research trials, contributing to valuable evidence for personalized rehabilitation medicine for older Veterans. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06451874
Study type Interventional
Source VA Office of Research and Development
Contact Elisa Ogawa, PhD MS BS
Phone (857) 364-4011
Email elisa.ogawa@va.gov
Status Not yet recruiting
Phase N/A
Start date January 1, 2025
Completion date December 31, 2029

See also
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Enrolling by invitation NCT04115215 - Pre-FRONTal Brain STability, Key for Action Against Disability in AGing N/A
Recruiting NCT04492241 - Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution for the Treatment of Motoric Cognitive Risk Syndrome N/A
Recruiting NCT05640141 - Pre-demential Motoric Cognitive Risk Syndrome in Ageing Subjects
Active, not recruiting NCT04240028 - The Cognitive-Prefrail Syndrome and Its Association With Adverse Health Outcomes
Completed NCT03750682 - ENGAGE for Brain Health N/A
Active, not recruiting NCT04275817 - Cognitive Prefrail and Frailty, and Motoric Cognitive Risk Syndrome: Prevalence and Association With Incident Adverse Health Events