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Motor Neurone Disease clinical trials

View clinical trials related to Motor Neurone Disease.

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NCT ID: NCT05292690 Completed - Stroke Clinical Trials

An Assistive Powered Wheelchair: Stage 2 Trial

EDUCAT
Start date: March 29, 2021
Phase:
Study type: Observational

Preliminary evaluation of an obstacle alerting system to enhance the user's independent mobility by improving their confidence to drive and their safety in driving a powered wheelchair.

NCT ID: NCT03444428 Completed - Clinical trials for Motor Neurone Disease

The Relationship Between Arterial Stiffness and Respiratory Failure in Motor Neurone Disease

Start date: February 21, 2017
Phase:
Study type: Observational

- Patients with Motor Neurone Disease (MND) admitted to Lane Fox Unit /Royal Brompton Hospital and/or reviewed in Lane Fox Unit /Royal Brompton Hospital clinics and/or outreach review will be approached for participation in the study - Physiological assessment and measurement of arterial stiffness will be performed in all patients at baseline and after the use of non invasive ventilation for 6 weeks. - MND patients not requiring mechanical ventilation will serve as controls since non invasive ventilation cannot be withheld from MND patients in type II respiratory failure. - Data will be analysed to look for differences between groups, relationships in baseline or change from baseline in respiratory physiological measures, inflammatory indices, breathlessness, and arterial stiffness. - Age, Height, Weight - History and Physical Examination - Evaluation of dysponea: mMRC, Borg Scale (Seated-Supine) - Amyotrophic lateral sclerosis functional rating scale (ALSFRS-R) - Sleep Disordered Breathing in Neuromuscular Disease Questionnaire (SiNQ-5) - 24 hour blood pressure monitor - Carotid-femoral pulse wave velocity - Respiratory Muscle Strength - Maximal Inspiratory Pressure, Maximal Expiratory Pressure, and Sniff Nasal Inspiratory Pressure - Spirometry - FEV1 and FVC - Arterial Blood Gas - CRP and fibrinogen (clinically) - Breathe CO exhale

NCT ID: NCT02464852 Completed - Clinical trials for Motor Neurone Disease

Assessment of the Effects of Sheffield Support Snood in MND Patients

Start date: April 2015
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effects on MND patients of a new collar specifically designed for people affected by neck weakness: the Sheffield Support Snood.