Comparison of Care Practices, Mortality and Morbidity of Very Preterm Infants Between Two Tertiary Centers in Northwest and South of China

Morality Clinical Trial

Official title:

Comparison of Care Practices, Mortality and Morbidity of Very Preterm Infants Between Two Tertiary Centers in Northwest and South of China

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05116670
• Other study ID #: NMU-FY2021-58
• Status: Completed
• Start date: October 15, 2021
• Est. completion date: December 31, 2021

Study information

• Verified date: February 2022
• Source: Nanjing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Care practices, mortality and morbidity of very premature infants from two different tertiary centers were collected and compared, in order to discover areas for improvement where these two newborn centers can learn from each other.

Description:

This retrospective cohort study was conducted in two hospitals,Qinghai Red Cross Hospital and Jinan University affiliated Shenzhen Baoan Women's and Children's Hospital.Very premature infants born with a gestational age between 22+0 - 31+6 weeks admitted to both centers during 3 years from January 1, 2018 to December 31, 2020 were studied. In both centers, data including maternal characteristics, neonatal characteristics, obstetric practices, delivery room practices, and neonatal outcomes, were collected by data abstractors in each NICU. Anonymous data was transferred to Shenzhen and analyses were performed at the newborn center of SZH.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 807
• Est. completion date: December 31, 2021
• Est. primary completion date: December 31, 2021
• Gender: All
• Age group: N/A to 28 Days

Eligibility

Inclusion Criteria:

• Very premature infants born with a gestational age between 22+0 - 31+6 weeks;

• Admitted to both centers during 3 years from January 1, 2018 to December 31, 2020.

Exclusion Criteria:

• Infants not born at QHH or SZH (out born);

• Infants who had major congenital anomalies;

• Infants admitted after 7 days of life.

Related Conditions & MeSH terms

• Morality
• Morbidity;Newborn
• Premature Birth
• Very Preterm Maturity of Infant

Locations

Country	Name	City	State
China	Shenzhen Baoan Women's and Children's Hospital	Shenzhen	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Nanjing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mortality	death during hospitalisation and death after withdrawing treatment	Jan 1,2018 - Dec 31,2020
Primary	Major morbidity	severe neurological injury, moderate to severe BPD, NEC or severe ROP	Jan 1,2018 - Dec 31,2020