Model-based Iterative Reconstruction (MB-IR VEOTM) Clinical Trial
Official title:
Model-based Iterative Reconstruction (MB-IR VEOTM) in Ultra Low-dose Abdominal CT Versus Adaptative Statistical Iterative Reconstruction (ASIR): A Prospective Study for Acute Renal Colic
The purpose of this study is to determine if Model-based iterative reconstruction (MB-IR VEOTM) in ultra low-dose abdominal CT as the same accuracy for the diagnosis of acute renal colic versus standard CT with adaptative statistical iterative reconstruction (ASIR).
Renal colic is a common recurrent pathology in young patients, multi explored by imaging
such as CT and abdominal radiography.
Abdominal MDCT(MultiDetector Computed Tomography) without injection is the gold standard in
diagnosis of acute flank pain suspect of renal colic due to high sensitivity (96%) and
excellent specificity (100%).
The increased use of medical imaging examinations using ionizing radiation (+57 % between
2002 and 2007) makes it essential to optimize protocols, including CT-scans which represents
10.1 % of procedures and 58 % of the collective effective dose.
Model-based iterative reconstruction (MB-IR VEOTM) (GE Healthcare, Milwaukee, WI) can use a
low dose acquisition, reducing the effective dose delivered to the patient almost 80%
comparing a standard CT with the last algorithm: adaptative statistical iterative
reconstruction (ASIR).
MB-IR VEOTM shows great potential for substantially reducing radiation doses at routine
abdominal CT. ASIR is limited in this regard owing to reduced image quality and diagnostic
capability. Further investigation is needed to determine the optimal dose level for
MBIR(Model Base Iterative Reconstruction) that maintains adequate diagnostic performance. In
general, objective and subjective image quality measurements do not necessarily correlate
with diagnostic performance at ultralow-dose CT.
Objective:
Prospective clinical study, equivalence between two CT protocols for the diagnosis of acute
renal colic.
Show that a low dose acquisition with model based iterative reconstruction (MB-IR VeoTM) is
as good as a standard CT with adaptative statistical iterative reconstruction (ASIR) in the
diagnosis acute renal colic
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic