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Mitral Valve Insufficiency clinical trials

View clinical trials related to Mitral Valve Insufficiency.

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NCT ID: NCT04382612 Terminated - Clinical trials for Mitral Regurgitation

Treatment of Mitral Regurgitation Using a Minimally Invasive Approach With the HARPOON Device.

ASCEND
Start date: October 2, 2020
Phase: N/A
Study type: Interventional

To evaluate the long-term safety and performance of the HARPOON™ MVRS for use in patients presenting with severe degenerative mitral regurgitation due to posterior leaflet prolapse in the post-market phase.

NCT ID: NCT04375332 Active, not recruiting - Clinical trials for Mitral Regurgitation

Beating Heart Mitral Valve Repair With the HARPOON™ System

RESTORE
Start date: December 16, 2020
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the safety and effectiveness of the HARPOON™ System in the treatment of patients with severe degenerative mitral regurgitation (DMR).

NCT ID: NCT04351984 Completed - Clinical trials for Mitral Regurgitation

Transcatheter Mitral Valvuloplasty Pilot Study

MitraClip
Start date: October 20, 2020
Phase:
Study type: Observational

This study is to evaluate the efficacy and safety of Transcatheter Mitral Valvuloplasty for Severe Mitral Regurgitation

NCT ID: NCT04350372 Completed - Clinical trials for Functional Mitral Regurgitation

MitraClip Russia Trial

Start date: February 18, 2020
Phase: N/A
Study type: Interventional

The MitraClip System is the first commercially available catheter-based option for the treatment of MR. The MitraClip System was developed as an alternate percutaneous technology which may serve as a viable therapeutic option for patients at high risk for open-heart surgery. Treatment with the MitraClip device allows patients to undergo a less invasive procedure that can mechanistically reduce MR and allow for improved quality of life. The MitraClip procedure is performed under general anesthesia without the use of a heart-lung machine, with recovery typically lasting two to three days. The objective of this study is to evaluate safety and effectiveness of the MitraClip NT procedure in the Russian population for treatment of Mitral Regurgitation.

NCT ID: NCT04343313 Recruiting - Clinical trials for Mitral Valve Insufficiency

The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study

Start date: December 8, 2020
Phase: N/A
Study type: Interventional

The study is a prospective, multi-center, single-arm, non-randomized, Early Feasibility Study (EFS) to evaluate the safety and performance of the Half Moon TMVr System in patients with severe, symptomatic mitral regurgitation, who are at high risk for conventional mitral valve surgery.

NCT ID: NCT04299334 Not yet recruiting - Clinical trials for Mitral Regurgitation

Neochordae Technique in Mitral Valve Repair

Start date: March 2, 2020
Phase: Phase 1
Study type: Interventional

Mitral valve (MV) repair has turned into a preferable option for surgeons over the MV replacement. Since the 1960s, Surgeons use this technique for more efficiency and durability. On the other hand, the proper determination of length and placement of artificial neochordae is still a challenge beyond this technique. These challenges are still a vital area for research and debate between surgeons and researchers. In our novel technique,Investigators are not depending either on the preoperative investigations or intraoperative reference chordae in the adjustment of the optimal length of the neochordae, however, Researchers depend on the personal adjustment of the chordal length to the prolapsed scallop.

NCT ID: NCT04293575 Recruiting - Heart Failure Clinical Trials

Transcatheter Mitral Valve Repair as Bridge Therapy to Heart Transplantation

MitraBridge
Start date: June 1, 2018
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to report medium-term outcomes after the use of transcatheter mitral valve repair (TMVR) with MitraClip as a bridge therapy to heart transplantation (HTx) in patients with mitral regurgitation (MR) and end-stage heart failure (HF).

NCT ID: NCT04281940 Active, not recruiting - Clinical trials for Mitral Valve Regurgitation

Chordal Repair for Transcatheter Mitral Valve Repair (TMVr)

Start date: March 18, 2022
Phase: N/A
Study type: Interventional

A multi-center evaluation of the Pipeline chordal repair system for treatment of clinically significant mitral regurgitation in subjects determined appropriate for mitral valve repair.

NCT ID: NCT04279678 Not yet recruiting - Clinical trials for Moderate Ischemic Mitral Regurgitation

Surgical Strategies in Moderate Ischemic Mitral Insufficiency in Patients Undergoing Coronary Artery Bypass Graft

Start date: March 2020
Phase:
Study type: Observational

Ischemic mitral regurgitation (IMR) is a common complication of myocardial infarction, with a reported prevalence of 13-59%. Approximately one-third of these patients have at least moderate MR .

NCT ID: NCT04259411 Active, not recruiting - Clinical trials for Mitral Regurgitation

MitraClip China PMS

Start date: December 6, 2021
Phase: N/A
Study type: Interventional

The MitraClip System is the first commercially available catheter-based option for the treatment of MR. The MitraClip System was developed as an alternate percutaneous technology which may serve as a viable therapeutic option for open-heart surgery. Treatment with the MitraClip device allows patients to undergo a less invasive procedure that can mechanistically reduce MR and allow for improved quality of life. The MitraClip procedure is performed under general anesthesia without the use of a heart-lung machine, with recovery typically lasting two to three days.