Anesthesia in Patients With Mitochondrial Disease

Status Recruiting

Clinical Trial Summary

This pilot study is a prospective, randomized clinical trial to evaluate the effect of anesthesia in the mitochondrial dysfunction patient.

Clinical Trial Description

Study subjects undergoing a routine medical care non-emergent procedure will be randomized into three different groups to receive one of the following anesthetic agents; Sevoflurane, Propofol or Dexmedetomidine.

The primary outcome of this pilot study is to evaluate and compare the incidence of adverse events in mitochondrial patients undergoing a diagnostic or therapeutic procedure up to 48 hours post anesthesia. The secondary outcome is to compare the metabolic derangements between three study groups by comparing changes in blood sugar, serum pH, serum bicarbonate, serum lactate and serum pyruvate levels before, during and after anesthesia in the groups. ;

Study Design

Related Conditions & MeSH terms

Mitochondrial Diseases

Clinical Trial Details

NCT number	NCT02053766
Study type	Interventional
Source	The University of Texas Health Science Center, Houston
Contact	Stephanie Maldonado
Phone	713-828-4291
Email	Stephanie.Maldonado@uth.tmc.edu
Status	Recruiting
Phase	N/A
Start date	January 10, 2014
Completion date	September 2022

View Details

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