Mechanisms of Mitochondrial Defects in Gulf War Syndrome

Gulf War Syndrome Clinical Trial

Official title: Mechanisms of Mitochondrial Defects in Gulf War Syndrome

Status Completed

Clinical Trial Summary

The purpose of the study is to investigate possible causes for Gulf War Syndrome. Gulf War Syndrome is associated with increased incidences of amyotrophic lateral sclerosis (Lou Gehrig's Disease), pain syndromes, muscle complaints that include fatigue and myalgias (muscle pain), as well as other neurological symptoms. Abnormalities in the part of the cell known as mitochondria have been delineated in Gulf War Syndrome. Mitochondria are the "power plants" of the body. Mitochondria take the food you eat and break the food down into a form of energy that the body can use. The investigators propose that Gulf War Syndrome is determined by a complex interaction of factors that interfere with mitochondrial function. This study will be the first investigation of mitochondrial function in Gulf War Syndrome. The investigators objective is to establish the cause for symptoms in affected veterans, develop testing that can more easily identify Gulf War Syndrome, and ultimately develop treatment protocols for Gulf War Syndrome.

Clinical Trial Description

n/a

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Gulf War Syndrome
• Mitochondrial Disease
• Mitochondrial Diseases
• Persian Gulf Syndrome
• Syndrome

• NCT number: NCT01264471
• Study type: Observational
• Source: Medical Neurogenetics, LLC
• Status: Completed
• Phase: N/A
• Start date: May 2009
• Completion date: June 2013