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Letrozole Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion

Missed Abortion Clinical Trial

Official title:
Letrozole Pretreatment With Misoprostol for Induction of Abortion In First-Trimester Missed Miscarriage: A Randomized Controlled Trial

Clinical Trial Summary

This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy.

Clinical Trial Description

According to the American college of obstetricians and gynecologists (2005), medical abortion is an acceptable alternative for surgical procedures in pregnant women with gestational age of less than 49 days based on the last menstrual period

Oral or vaginal misoprostol causes complete abortion in almost 85% of cases within seven days before the 12th week

letrozole administration with misoprostol raises the rate of complete abortion ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04217265
Study type Interventional
Source Cairo University
Contact AHMED SAMY
Phone +201100681167
Email ahmedsamy8233@gmail.com
Status Not yet recruiting
Phase Phase 4
Start date January 5, 2020
Completion date April 10, 2020
View Details
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Completed NCT02686840 - Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage Phase 3
Terminated NCT02342002 - Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled Trial Phase 4
Recruiting NCT01775917 - The Role of Uterine Artery Doppler Parameters in the Management of Retained Products of Conception. N/A
Active, not recruiting NCT04593108 - Misoprostol With or Without Letrozole in Treatment of Missed Miscarriage