Missed Abortion Clinical Trial
Official title:
Study at Zagazig General Hospital
Aim of study Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester. Hypothesis: Letrozole value as a pre-treatment medication for misoprostol in induction of abortion during the first trimester. Research question: Will letrozole- misoprostol protocol give better results than misoprostol- alone protocol in induction of abortion during the first trimester?
Aim of the Work Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester. Hypothesis: Letrozole value as a pre-treatment medication for misoprostol in induction of abortion during the first trimester. Research question: Will letrozole- misoprostol protocol give better results than misoprostol- alone protocol in induction of abortion during the first trimester? Primary outcome: Complete abortion (complete expulsion of products of conception with no need for curettage) within one week from the first dose of misoprostol. Secondary outcome: • Curettage (surgical evacuation of the products of conception) - Incomplete abortion (retained products of conception). - Considerable bleeding that necessitates immediate evacuation. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT01639976 -
Doppler Flow Measurements in Patients With Misoprostol Treatment for Arrested Pregnancy
|
N/A | |
| Recruiting |
NCT03628625 -
Letrozole Pretreatment With Misoprostol fInduction of Abortion In First-Trimester Missed Miscarriage
|
Phase 2 | |
| Completed |
NCT03584698 -
Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed Miscarriage
|
Phase 4 | |
| Recruiting |
NCT05516810 -
The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles
|
||
| Not yet recruiting |
NCT04590482 -
Letrozole Pretreatment With Misoprostol Induction of Abortion in First Trimester Missed Abortion
|
Phase 4 | |
| Recruiting |
NCT05342467 -
Gemeprost Versus Dinoprostone in First Trimester Miscarriages
|
Phase 2 | |
| Recruiting |
NCT03698734 -
Evening Primrose Oil Efficacy in Second Trimester Abortion
|
Phase 3 | |
| Terminated |
NCT01615224 -
Repeated Doses of Misoprostol for Medical Treatment of Missed Miscarriage
|
Phase 2/Phase 3 | |
| Completed |
NCT05216952 -
Ulipristal Acetate for Use in Early Pregnancy Loss
|
Phase 2 | |
| Recruiting |
NCT03081104 -
Operative Hysteroscopy and Ultrasound Guided Vacuum Aspiration Versus Blind Vacuum Aspiration for the Treatment of Missed Abortion
|
N/A | |
| Completed |
NCT00892229 -
Buccal Versus Vaginal Misoprostol in Surgical Termination of the First Trimester Missed Abortion in Erbil
|
Phase 2 | |
| Active, not recruiting |
NCT04981457 -
Comparative Study Between Combined Vaginal Misoprostol
|
Phase 1 | |
| Recruiting |
NCT02573051 -
Termination Of Anembryonic Pregnancy
|
Phase 2 | |
| Not yet recruiting |
NCT04215835 -
Letrozole Pretreatment With Misoprostol Induction of Abortion In First-Trimester Missed Miscarriage
|
Phase 4 | |
| Not yet recruiting |
NCT04217265 -
Letrozole Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
|
Phase 4 | |
| Recruiting |
NCT04705324 -
Dilation and Curettage Versus Operative Hysteroscopy for Missed Abortion
|
N/A | |
| Completed |
NCT02686840 -
Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage
|
Phase 3 | |
| Terminated |
NCT02342002 -
Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled Trial
|
Phase 4 | |
| Recruiting |
NCT01775917 -
The Role of Uterine Artery Doppler Parameters in the Management of Retained Products of Conception.
|
N/A | |
| Not yet recruiting |
NCT05001061 -
Sublingual vs Vaginal Misoprostol for Termination of First Trimesteric Missed Abortion
|
Early Phase 1 |