Miscarriage Clinical Trial
Official title:
Letrozole Pretreatment With Misoprostol for Induction of Abortion In First-Trimester Missed Miscarriage: A Randomized Controlled Trial
This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first trimester pregnancy.
Status | Recruiting |
Enrollment | 80 |
Est. completion date | December 10, 2018 |
Est. primary completion date | December 5, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Gestational age less than 64 days gestation (<9 wks). - Hemoglobin >10 g/dL. - BMI between 18.5 kg/m2 and 25 kg/m2. - Missed abortion. Exclusion Criteria: - Molar pregnancy. - Fibroid uterus. - Uterine anomalies. - Coagulopathy. - Medical disorder that contraindicate induction of abortion (e.g. heart failure). - Previous attempts for induction of abortion in the current pregnancy. - Allergy to misoprostol or letrozole. |
Country | Name | City | State |
---|---|---|---|
Egypt | Ain Shams University, Maternity Hospital | Cairo |
Lead Sponsor | Collaborator |
---|---|
Ain Shams Maternity Hospital |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Incidence of complete miscarriage | 6 hours | ||
Secondary | Need for surgical evacuation of the products of conception | 6 hours | ||
Secondary | Incidence of Septic Abortion | 1 week |
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