Miscarriage Clinical Trial
Official title:
Letrozole Pretreatment With Misoprostol for Induction of Abortion In First-Trimester Missed Miscarriage: A Randomized Controlled Trial
This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first trimester pregnancy.
According to the American college of obstetricians and gynecologists (2005), medical abortion
is an acceptable alternative for surgical procedures in pregnant women with gestational age
of less than 49 days based on the last menstrual period
Oral or vaginal misoprostol causes complete abortion in almost 85% of cases within seven days
before the 12th week
letrozole administration with misoprostol raises the rate of complete abortion
Hypothesis:
In women with missed miscarriage in the first trimester undergoing induction of abortion
pre-treatment with letrozole before misoprostol may lead to abortion rate similar to
misoprostol alone.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05969574 -
Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?
|
||
| Enrolling by invitation |
NCT01689428 -
Ism1 Versus EmbryoGen Media for Embryo Culture in Previous Pregnancy Loss Cases
|
Phase 3 | |
| Completed |
NCT00194844 -
Couples Miscarriage Healing Project:Randomized Trial
|
Phase 1/Phase 2 | |
| Recruiting |
NCT05789940 -
Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic Retention
|
N/A | |
| Not yet recruiting |
NCT05579756 -
Psychatric Impact of Miscarriage in Assiut University Hospital
|
||
| Not yet recruiting |
NCT05557201 -
Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism Factors
|
||
| Not yet recruiting |
NCT05039853 -
Improving Mental Health Following Early PREgnancy Loss Using a Brief Cognitive Task
|
N/A | |
| Recruiting |
NCT01223482 -
A Study Looking at Women's Experiences After a Miscarriage
|
N/A | |
| Completed |
NCT04604366 -
Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage
|
Phase 2 | |
| Not yet recruiting |
NCT05094375 -
Vaginal Misoprostol In Medical Treatment of First Trimester Missed Miscarriage
|
N/A | |
| Not yet recruiting |
NCT05088720 -
Misoprostol for Management of Women With an Incomplete Miscarriage
|
N/A | |
| Not yet recruiting |
NCT05088707 -
Sublingual Versus Vaginal Misoprostol In Medical Treatment of Second Trimestric Missed Miscarriage
|
N/A | |
| Not yet recruiting |
NCT05103098 -
Sublingual Misoprostol In Medical Treatment of First Trimester Missed Miscarriage
|
N/A | |
| Recruiting |
NCT05304273 -
Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages
|
Phase 3 | |
| Not yet recruiting |
NCT05653414 -
Interest of a Short Early Psychological Care in Women With Miscarriage
|
N/A | |
| Recruiting |
NCT03976544 -
Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients
|
Phase 4 | |
| Completed |
NCT01916928 -
The Use of Cell Free Fetal DNA in the Maternal Blood in the Evaluation of Intrauterine Fetal Demise and Miscarriage
|
N/A | |
| Completed |
NCT03940495 -
Serum Kisspeptin: a Predictive Marker of Miscarriage or Not?
|
||
| Completed |
NCT04512820 -
Treatment of Missed Miscarriage With TRUCLEAR Tissue Removal System, a Feasiblity Study
|
N/A | |
| Recruiting |
NCT05762770 -
A Trial of Sperm Injection (PICSI) on Miscarriage Rates in Assisted Conception
|
N/A |