Mild Traumatic Brain Injury Clinical Trial
Official title:
Photobiomodulation for Concussions: the Use of the ImPACT® Test to Assess Improvement in Cognition and Symptomatology
Brain photobiomodulation (PBM) therapy is an innovative modality for the stimulation of neural activity in order to improve brain function and is currently under investigation as a treatment for several diverse neurological disorders. Our emphasis on this study is to review the use of PBM as a treatment modality for concussions and the use of ImPACT® (Immediate Post-Concussion Assessment and Cognitive Testing) test to assess improvement in cognition and symptomatology in patients with post-concussion syndrome (PCS) treated with PBM.
- This will be a retrospective, single arm, unmasked, clinical study. - Data scores will be collected for patients who initially underwent the Workplace Post-Injury 1 test of the ImPACT® test system prior to PBM treatment. - Patients were treated with photobiomodulation using the BIOFLEX® DUO+ system that utilized a 180 bulb Light Emitting Diode (LED) array followed by laser probes. Both delivery methods were applied to the cervical spine and the cranium, and both entailed the use of red light at 660 nm wavelength and near-infrared light at 830-840 nm wavelength. Treatment is provided three times per week on alternating days with weekends off for 4 weeks for a total of 12 treatments utilizing Health Canada approved device specific protocol guidelines for treatment of the cervical spine. - Data scores will be collected for a second ImPACT® test using the Workplace Post-Injury 2 test. - Results of the Post-Injury 1 test and the Post-Injury 2 test will be compared. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04372797 -
Standardized Instruments to Provide Diagnostic and Prognostic Information in Mild Traumatic Brain Injury (mTBI)
|
N/A | |
| Completed |
NCT01903525 -
DHA For The Treatment of Pediatric Concussion Related to Sports Injury
|
Phase 1 | |
| Completed |
NCT01847040 -
Deployment Related Mild Traumatic Brain Injury (mTBI)
|
||
| Completed |
NCT03678077 -
Trends in Cohabitation Status, Academic Achievement and Socio-economic Indicators After Mild Traumatic Brain Injury
|
||
| Recruiting |
NCT05682677 -
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
|
N/A | |
| Terminated |
NCT03345550 -
OPTIMA-TBI Pilot Study
|
Phase 2 | |
| Completed |
NCT05095012 -
RECOVER Clinical Pathway for Pediatric Concussion
|
N/A | |
| Recruiting |
NCT05886400 -
The Effects of Environmental Distractions on SCAT6 Outcomes
|
N/A | |
| Recruiting |
NCT05262361 -
Persistent Post-Concussion Symptoms With Convergence Insufficiency
|
N/A | |
| Active, not recruiting |
NCT03892291 -
Objective Dual-task Turning Measures for Return-to-duty Assessments
|
||
| Completed |
NCT03688984 -
Treatment of Insomnia for Adolescents With Mild Traumatic Brain Injury
|
N/A | |
| Completed |
NCT02057081 -
Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI
|
N/A | |
| Recruiting |
NCT06233851 -
t-BIOMAP : Prospective Paediatric Cohort Study of Blood Biomarkers in mTBI
|
||
| Completed |
NCT02844946 -
One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology
|
N/A | |
| Completed |
NCT04641767 -
BIOmarkers of TRAumatic Brain Injury Spain (BIOTRABIS)
|
||
| Recruiting |
NCT06112093 -
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
|
N/A | |
| Recruiting |
NCT03819608 -
Neuromodulation and Neurorehabilitation for mTBI Plus PTSD
|
N/A | |
| Withdrawn |
NCT00580918 -
Functional MRI Study of Attention in Normal Controls and Traumatic Brain Injured Patients
|
||
| Completed |
NCT03319966 -
Eyetracking and Neurovision Rehabilitation of Oculomotor Dysfunction in Mild Traumatic Brain Injury
|
||
| Recruiting |
NCT03846830 -
Incremental Velocity Error as a New Treatment in Vestibular Rehabilitation
|
N/A |