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Cognitive Effects of Roflumilast in (a)MCI and Mild Dementia Patients — ROMEMA  

Mild Cognitive Impairment Clinical Trial

Official title:
A Proof of Concept Phase II Study With the PDE4 Inhibitor Roflumilast in Patients With (Amnestic) Mild Cognitive Impairment (MCI) or Mild Dementia

Clinical Trial Summary

The aim of the current project is to validate whether chronic intake (24 weeks) roflumilast (PDE4 inhibitor) can improve cognition in patients with (amnestic) mild cognitive impairment (MCI) and in patients with mild dementia. The project will demonstrate whether episodic memory, but also attention, information processing or executive function improves with chronic administration of roflumilast in (a)MCI and mild dementia patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04658654
Study type Interventional
Source Maastricht University Medical Center
Contact Nina Possemis, MSc.
Phone +31 (0)43 388 1022
Email n.possemis@maastrichtuniversity.nl
Status Recruiting
Phase Phase 2
Start date November 19, 2021
Completion date October 2023
View Details
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