Mild Cognitive Impairment, So Stated Clinical Trial
Official title:
Impact of Transcranial Slow Oscillating Stimulation on Memory Consolidation During Nocturnal Slow Wave Sleep in Patients With Mild Cognitive Impairments(MCI)
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent declarative memory. Slow oscillatory activity typically occuring during SWS has been implicated in the consolidation effect. Recent evidence in young healthy subjects suggest that the sleep-associated consolidation effect can be amplified by the application of a weak transcranial oscillatory electric current within the frequency range of SWS in humans (0,7-0,8 Hz) during SWS. If patients with amnestic mild cognitive impairments (MCI)- usually characterized by initial difficulties in hippocampus dependent memory functions - benefit from transcranial slow oscillatory stimulation (tSOS) during nocturnal sleep as well has not been studied so far. The primary aim of the present study is to investigate the influence of a weak slow oscillating brain stimulation (tSOS) on declarative memory consolidation applied during periods of nocturnal SWS in MCI patients.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02313935 -
Cognitive/Physical Computer-Game Blended Training of Elderly: Neuroscientific LLM Studies
|
N/A | |
Completed |
NCT03686839 -
Feasibility Study of Neurofeedback Training for Older Adults With Mild Cognitive Impairment
|
N/A | |
Completed |
NCT01684293 -
Occupational Therapy-Based Cognitive Rehabilitation of Cocaine Abusers: A Pilot Study
|
N/A | |
Completed |
NCT00422981 -
Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment
|
Phase 2 | |
Completed |
NCT02417558 -
Cognitive/Physical Computer-Game Blended Training With Personalized Brain Network Activation Technology for the Elderly
|
N/A | |
Completed |
NCT03195829 -
Feasibility Study of a Computerized Cognitive Stimulation
|
N/A | |
Completed |
NCT01782365 -
Effects of Brain Stimulation During a Daytime Nap on Memory Consolidation in Patients With Mild Cognitive Impairment
|
N/A |