Migraine Clinical Trial
Official title:
Registry of Right-to-left Shunt Detection by Contrast-enhanced Transcranial Doppler in Chinese Population
The purpose of the study is to evaluate the prevalence and extent of right-to-left shunt (RLS) in Chinese migraineurs, and the morbidity of silent cerebral infarction in migraineurs.
This is a prospective multicenter study of Chinese population. Participants (normal
individuals without migraine and migraineurs) are included after standardized diagnostic
procedures (TCD and c-TCD). For migraineurs with large RLS further examinations (c-TTE and
brain MRI) are required. Up to 10 study sites nationwide will be needed to recruit the
planned participant population during a 1-year period.
The information of each participants will be registered, including basic facts, the
longitudinal headache history, frequency, location, quality, intensity, duration, accompanied
symptoms, precipitating and exacerbating factors, with or without aura, MIDAS and HIT-6
questionnaire.
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