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Clinical Trial Summary

Migraine is a highly disabling disorder that affects hundreds of millions of people around the world. Yet, a little number of prophylactic treatments are available still now. The limited number of available drugs leads to a wide use of nutraceutical compounds in migraine therapy. To improve the efficacy, some of these nutraceuticals were combined. So far, we do not know if these combinations are really more effective than the single compounds alone, or an anti-synergic effect could be present because of a reciprocal antagonism of effects. For this reason, we decided to test the efficacy of a fixed combination of magnesium, partenium, andrographis, co-enzyme Q10 and riboflavin (PACR) as prophylactic treatment for migraine in a randomized controlled double blind study.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03190044
Study type Interventional
Source University of Roma La Sapienza
Contact Cherubino Di Lorenzo, PhD
Phone +393286783246
Email cherubino.dilorenzo@uniroma1.it
Status Recruiting
Phase N/A
Start date June 6, 2017
Completion date December 31, 2019

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