Migraine Disorders Clinical Trial
Official title:
Non-steroidal Anti-inflammatory Drugs Alone or With a Triptan and Reports of Transition From Episodic to Chronic Migraine
Chronic Migraine (CM), or 15 or more migraine headaches per month, is common in tertiary
headache care and is associated with a number of deleterious outcomes, especially higher
disability and poorer quality of life, relative to those with Episodic Migraine (EM) defined
as 14 or fewer migraine headaches per month. Limited work has begun to examine factors that
increase or decrease the risk of developing CM. One factor that appears especially relevant
is symptomatic medication use. The current study builds upon and expands previous work
considering the influence non-steroidal anti-inflammatory drug (NSAID) and/or triptan use
has on the likelihood of developing CM.
This study is a retrospective observational cohort study of data collected via mail survey
and collated in the American Migraine Prevalence and Prevention (AMPP) database.
Survey results from the AMPP study will be analyzed retrospectively. The AMPP is a
longitudinal, population-based, mailed-questionnaire survey. In 2004, 120,000 United States
(US) households were screened and 24,000 individuals who reported severe headaches were
identified and additional questionnaires have been administered annually. This analysis uses
data from respondents who meet second edition of the International Headache Classification-2
(IHCD-2) criteria for EM in 2005 with follow up results in 2006, 2007, 2008, and 2009. EM is
defined as 1 to 14 headaches per month and CM is defined as 15 or more headaches per month.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01432379 -
BOTOX® Prophylaxis in Patients With Chronic Migraine
|
||
| Completed |
NCT04084314 -
Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study
|
Phase 4 | |
| Recruiting |
NCT05048914 -
Migraine Abortive Treatment
|
||
| Completed |
NCT03662295 -
Stroke-like Migraine Attacks After Radiation Treatment (SMART) Syndrome Language Intervention
|
||
| Completed |
NCT02766517 -
Biomarker Study in Participants With Migraine
|
Early Phase 1 | |
| Completed |
NCT00963937 -
Study to Evaluate the Efficacy and Safety of Oral Sumatriptan for the Acute Treatment of Migraine in Children and Adolescents
|
Phase 3 | |
| Not yet recruiting |
NCT03632928 -
Day to Day Variation of Pressure Pain Threshold and Muscle Hardness
|
||
| Completed |
NCT02559895 -
A Multicenter Assessment of ALD403 in Frequent Episodic Migraine
|
Phase 3 | |
| Completed |
NCT00743015 -
Relative Bioavailability of a Single Dose of BI 44370 Tablet During and Between Migraine Attacks
|
Phase 1 | |
| Completed |
NCT01376141 -
Drug Use Investigation for IMIGRAN Tablet
|
N/A | |
| Completed |
NCT02183688 -
Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients
|
Phase 3 | |
| Completed |
NCT03588364 -
The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine
|
N/A | |
| Completed |
NCT04091321 -
Association Between Chronic Headache and Back Pain With Childbirth
|
||
| Completed |
NCT00385008 -
TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine
|
Phase 3 | |
| Active, not recruiting |
NCT05888298 -
Proximal and Distal Approach GON RFT in Migraine
|
N/A | |
| Completed |
NCT03435185 -
Greater Occipital and Supraorbital Nerve Blockade in Migraine Patients
|
N/A | |
| Completed |
NCT02565186 -
An Open-label, Long-term, Safety Study of Lasmiditan for the Acute Treatment of Migraine
|
Phase 3 | |
| Recruiting |
NCT06061588 -
"Potential Effects of Virtual Reality Technology on the Treatment of Migraine-Type Headaches"
|
N/A | |
| Completed |
NCT05658185 -
Migraine Difficult to Treat: the Importance of Psychological Care in the Chronic Patient
|
N/A | |
| Recruiting |
NCT06154070 -
An Open Label, Study of DaxibotulinumtoxinA for Migraine Prevention
|